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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP26A1
All Species:
11.82
Human Site:
S261
Identified Species:
23.64
UniProt:
O43174
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43174
NP_000774.2
497
56199
S261
K
I
C
G
L
R
A
S
E
A
G
Q
G
C
K
Chimpanzee
Pan troglodytes
XP_001147866
497
56210
S261
K
I
C
G
L
R
T
S
E
A
G
Q
G
C
K
Rhesus Macaque
Macaca mulatta
XP_001091435
497
56192
S261
K
I
C
G
L
R
A
S
E
A
G
R
G
C
K
Dog
Lupus familis
XP_849374
497
56167
A261
K
I
C
G
L
R
T
A
Q
A
G
G
G
C
K
Cat
Felis silvestris
Mouse
Mus musculus
O55127
497
56159
T261
K
I
R
R
L
Q
A
T
E
P
D
G
G
C
K
Rat
Rattus norvegicus
P24464
508
58540
R268
T
D
Q
V
I
K
S
R
K
A
Q
L
Q
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506310
540
59322
E258
H
M
E
A
V
I
A
E
K
L
R
A
G
P
G
Chicken
Gallus gallus
Q9PUB4
492
55246
K252
I
E
E
N
I
R
A
K
M
A
R
K
E
P
E
Frog
Xenopus laevis
O93323
492
55441
R255
N
I
K
E
K
L
Q
R
E
P
D
E
H
C
K
Zebra Danio
Brachydanio rerio
P79739
492
56262
N257
K
K
I
Q
D
D
D
N
E
N
E
Q
K
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGB4
493
56605
R237
G
L
E
W
L
R
R
R
D
A
S
A
I
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FH76
463
52348
N234
E
L
A
Q
I
L
A
N
I
L
S
K
R
R
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
94.9
N.A.
93.7
25.5
N.A.
42.4
79.4
67.6
68
N.A.
22.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
100
97.9
N.A.
96.7
41.7
N.A.
59.2
87.7
81.2
80.4
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
73.3
N.A.
53.3
6.6
N.A.
13.3
20
26.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
66.6
40
N.A.
33.3
40
33.3
33.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
50
9
0
59
0
17
0
0
0
% A
% Cys:
0
0
34
0
0
0
0
0
0
0
0
0
0
50
0
% C
% Asp:
0
9
0
0
9
9
9
0
9
0
17
0
0
9
0
% D
% Glu:
9
9
25
9
0
0
0
9
50
0
9
9
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
34
0
0
0
0
0
0
34
17
50
0
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
50
9
0
25
9
0
0
9
0
0
0
9
0
0
% I
% Lys:
50
9
9
0
9
9
0
9
17
0
0
17
9
0
67
% K
% Leu:
0
17
0
0
50
17
0
0
0
17
0
9
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
17
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
17
0
0
0
17
0
% P
% Gln:
0
0
9
17
0
9
9
0
9
0
9
25
9
0
9
% Q
% Arg:
0
0
9
9
0
50
9
25
0
0
17
9
9
9
0
% R
% Ser:
0
0
0
0
0
0
9
25
0
0
17
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _