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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP26A1
All Species:
33.33
Human Site:
S145
Identified Species:
66.67
UniProt:
O43174
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43174
NP_000774.2
497
56199
S145
K
V
I
M
R
A
F
S
R
E
A
L
E
C
Y
Chimpanzee
Pan troglodytes
XP_001147866
497
56210
S145
K
V
I
M
R
A
F
S
R
E
A
L
E
C
Y
Rhesus Macaque
Macaca mulatta
XP_001091435
497
56192
S145
K
V
I
M
R
A
F
S
R
E
A
L
E
C
Y
Dog
Lupus familis
XP_849374
497
56167
S145
K
V
I
M
R
A
F
S
R
E
A
L
Q
C
Y
Cat
Felis silvestris
Mouse
Mus musculus
O55127
497
56159
S145
K
V
I
M
Q
A
F
S
R
E
A
L
Q
C
Y
Rat
Rattus norvegicus
P24464
508
58540
H149
R
M
L
T
P
A
F
H
Y
D
T
L
K
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506310
540
59322
S155
R
V
L
S
Q
V
F
S
R
S
A
L
E
S
Y
Chicken
Gallus gallus
Q9PUB4
492
55246
S145
K
V
I
M
Q
A
F
S
R
D
A
L
Q
H
Y
Frog
Xenopus laevis
O93323
492
55441
S145
K
V
I
A
Q
A
F
S
R
E
A
L
A
N
Y
Zebra Danio
Brachydanio rerio
P79739
492
56262
S145
K
A
I
M
R
A
F
S
R
D
A
L
E
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGB4
493
56605
K135
K
H
M
N
P
A
F
K
H
S
V
L
L
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FH76
463
52348
M138
K
L
V
L
R
A
F
M
P
D
A
I
R
N
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
94.9
N.A.
93.7
25.5
N.A.
42.4
79.4
67.6
68
N.A.
22.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
100
97.9
N.A.
96.7
41.7
N.A.
59.2
87.7
81.2
80.4
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
26.6
N.A.
53.3
73.3
73.3
80
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
73.3
93.3
80
86.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
92
0
0
0
0
84
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
50
0
0
42
0
0
% E
% Phe:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
9
9
0
0
0
0
17
0
% H
% Ile:
0
0
67
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
84
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% K
% Leu:
0
9
17
9
0
0
0
0
0
0
0
92
9
0
0
% L
% Met:
0
9
9
59
0
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
17
0
0
0
9
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
34
0
0
0
0
0
0
0
25
0
0
% Q
% Arg:
17
0
0
0
50
0
0
0
75
0
0
0
9
0
0
% R
% Ser:
0
0
0
9
0
0
0
75
0
17
0
0
0
17
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
67
9
0
0
9
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
84
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _