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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP26A1 All Species: 22.42
Human Site: S132 Identified Species: 44.85
UniProt: O43174 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43174 NP_000774.2 497 56199 S132 L S N L H D S S H K Q R K K V
Chimpanzee Pan troglodytes XP_001147866 497 56210 S132 L S N L H D S S H K Q R K K V
Rhesus Macaque Macaca mulatta XP_001091435 497 56192 S132 L S N L H D S S H K Q R K K V
Dog Lupus familis XP_849374 497 56167 S132 L S N L H D S S H K Q R K K V
Cat Felis silvestris
Mouse Mus musculus O55127 497 56159 S132 L S N L H D S S H K Q R K K V
Rat Rattus norvegicus P24464 508 58540 T136 L L L L N G Q T W F Q H R R M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506310 540 59322 P142 L L G A V G E P H R Q R R R V
Chicken Gallus gallus Q9PUB4 492 55246 Q132 L S N L H N G Q H K H R K K V
Frog Xenopus laevis O93323 492 55441 E132 L S N L H D N E H K Y T K K V
Zebra Danio Brachydanio rerio P79739 492 56262 Q132 L S N V H G V Q H K N K K K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGB4 493 56605 K122 L L T L Q G S K W M A R R K H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FH76 463 52348 Y125 I F F H Q G D Y H S K L R K L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.5 94.9 N.A. 93.7 25.5 N.A. 42.4 79.4 67.6 68 N.A. 22.9 N.A. N.A. N.A.
Protein Similarity: 100 99.8 100 97.9 N.A. 96.7 41.7 N.A. 59.2 87.7 81.2 80.4 N.A. 43 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 33.3 73.3 73.3 53.3 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 53.3 N.A. 53.3 80 80 66.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 50 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % E
% Phe: 0 9 9 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 42 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 67 0 0 0 84 0 9 9 0 0 9 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 67 9 9 67 84 0 % K
% Leu: 92 25 9 75 0 0 0 0 0 0 0 9 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % M
% Asn: 0 0 67 0 9 9 9 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 17 0 9 17 0 0 59 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 67 34 17 0 % R
% Ser: 0 67 0 0 0 0 50 42 0 9 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 9 0 0 0 % T
% Val: 0 0 0 9 9 0 9 0 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _