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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP26A1
All Species:
20
Human Site:
S131
Identified Species:
40
UniProt:
O43174
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43174
NP_000774.2
497
56199
S131
C
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
Chimpanzee
Pan troglodytes
XP_001147866
497
56210
S131
C
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
Rhesus Macaque
Macaca mulatta
XP_001091435
497
56192
S131
C
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
Dog
Lupus familis
XP_849374
497
56167
S131
C
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O55127
497
56159
S131
C
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
Rat
Rattus norvegicus
P24464
508
58540
Q135
G
L
L
L
L
N
G
Q
T
W
F
Q
H
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506310
540
59322
E141
T
L
L
G
A
V
G
E
P
H
R
Q
R
R
R
Chicken
Gallus gallus
Q9PUB4
492
55246
G131
C
L
S
N
L
H
N
G
Q
H
K
H
R
K
K
Frog
Xenopus laevis
O93323
492
55441
N131
C
L
S
N
L
H
D
N
E
H
K
Y
T
K
K
Zebra Danio
Brachydanio rerio
P79739
492
56262
V131
T
L
S
N
V
H
G
V
Q
H
K
N
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGB4
493
56605
S121
G
L
L
T
L
Q
G
S
K
W
M
A
R
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FH76
463
52348
D124
A
I
F
F
H
Q
G
D
Y
H
S
K
L
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
94.9
N.A.
93.7
25.5
N.A.
42.4
79.4
67.6
68
N.A.
22.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
100
97.9
N.A.
96.7
41.7
N.A.
59.2
87.7
81.2
80.4
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
26.6
73.3
73.3
53.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
46.6
80
80
66.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
17
0
0
9
0
0
42
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
67
0
0
0
84
0
9
9
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
67
9
9
67
84
% K
% Leu:
0
92
25
9
75
0
0
0
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
67
0
9
9
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
0
9
17
0
0
59
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
67
34
17
% R
% Ser:
0
0
67
0
0
0
0
50
42
0
9
0
0
0
0
% S
% Thr:
17
0
0
9
0
0
0
0
9
0
0
0
9
0
0
% T
% Val:
0
0
0
0
9
9
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _