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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6A
All Species:
17.58
Human Site:
Y215
Identified Species:
42.96
UniProt:
O15550
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15550
NP_066963.2
1401
154177
Y215
Q
F
H
I
A
H
L
Y
E
T
Q
R
K
Y
H
Chimpanzee
Pan troglodytes
Q6B4Z3
1079
118013
Rhesus Macaque
Macaca mulatta
XP_001098278
1273
140201
K134
T
V
D
L
L
G
D
K
A
T
K
E
S
Y
A
Dog
Lupus familis
XP_850658
1401
154200
Y215
Q
F
H
I
A
H
L
Y
E
T
Q
R
K
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
O70546
1401
154336
Y217
Q
F
H
I
A
H
L
Y
E
T
Q
R
K
Y
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
L205
K
E
A
Y
E
Q
L
L
Q
T
E
N
L
P
A
Chicken
Gallus gallus
XP_416762
1384
152840
H205
Y
E
I
Q
R
K
Y
H
S
A
K
E
A
Y
E
Frog
Xenopus laevis
NP_001086774
1455
160368
Y217
Q
F
H
I
A
H
L
Y
E
T
Q
R
K
Y
H
Zebra Danio
Brachydanio rerio
XP_697746
1390
152664
Y217
Q
F
H
I
A
H
V
Y
E
I
Q
K
K
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
Q204
S
M
H
H
P
N
M
Q
N
K
S
K
T
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63
90.7
99
N.A.
97.3
N.A.
N.A.
91.2
92
84.2
75.5
N.A.
N.A.
N.A.
N.A.
34.2
Protein Similarity:
100
67.8
90.7
99.4
N.A.
98.2
N.A.
N.A.
93.9
95
89.3
82.9
N.A.
N.A.
N.A.
N.A.
48.1
P-Site Identity:
100
0
13.3
100
N.A.
100
N.A.
N.A.
13.3
6.6
100
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
0
26.6
100
N.A.
100
N.A.
N.A.
33.3
20
100
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
50
0
0
0
10
10
0
0
10
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
10
0
0
0
50
0
10
20
0
0
10
% E
% Phe:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
60
10
0
50
0
10
0
0
0
0
0
0
40
% H
% Ile:
0
0
10
50
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
0
10
0
10
20
20
50
0
0
% K
% Leu:
0
0
0
10
10
0
50
10
0
0
0
0
10
10
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
50
0
0
10
0
10
0
10
10
0
50
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
40
0
0
10
% R
% Ser:
10
0
0
0
0
0
0
0
10
0
10
0
10
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
60
0
0
10
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
10
50
0
0
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _