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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6A
All Species:
17.58
Human Site:
Y158
Identified Species:
42.96
UniProt:
O15550
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15550
NP_066963.2
1401
154177
Y158
K
A
F
Q
E
V
L
Y
V
D
P
S
F
C
R
Chimpanzee
Pan troglodytes
Q6B4Z3
1079
118013
Rhesus Macaque
Macaca mulatta
XP_001098278
1273
140201
F81
L
S
N
A
E
I
Q
F
H
I
A
H
L
Y
E
Dog
Lupus familis
XP_850658
1401
154200
Y158
K
A
F
Q
E
V
L
Y
V
D
P
S
F
C
R
Cat
Felis silvestris
Mouse
Mus musculus
O70546
1401
154336
Y160
K
A
F
Q
E
V
L
Y
V
D
P
S
F
C
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
V152
R
L
G
L
M
F
K
V
N
T
D
Y
E
S
S
Chicken
Gallus gallus
XP_416762
1384
152840
E151
P
S
F
C
R
A
K
E
I
H
L
R
L
G
L
Frog
Xenopus laevis
NP_001086774
1455
160368
Y160
R
A
F
Q
E
V
L
Y
V
E
P
S
F
C
R
Zebra Danio
Brachydanio rerio
XP_697746
1390
152664
Y160
K
A
F
Q
E
V
L
Y
I
D
P
C
F
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
D151
S
H
T
A
A
W
T
D
L
G
I
L
Y
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63
90.7
99
N.A.
97.3
N.A.
N.A.
91.2
92
84.2
75.5
N.A.
N.A.
N.A.
N.A.
34.2
Protein Similarity:
100
67.8
90.7
99.4
N.A.
98.2
N.A.
N.A.
93.9
95
89.3
82.9
N.A.
N.A.
N.A.
N.A.
48.1
P-Site Identity:
100
0
6.6
100
N.A.
100
N.A.
N.A.
0
6.6
86.6
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
26.6
100
N.A.
100
N.A.
N.A.
6.6
20
100
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
20
10
10
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
10
0
40
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
40
10
0
0
0
0
% D
% Glu:
0
0
0
0
60
0
0
10
0
10
0
0
10
10
10
% E
% Phe:
0
0
60
0
0
10
0
10
0
0
0
0
50
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
10
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
20
10
10
0
0
0
0
% I
% Lys:
40
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
10
0
0
50
0
10
0
10
10
20
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
10
0
0
0
0
0
0
10
0
0
50
% R
% Ser:
10
20
0
0
0
0
0
0
0
0
0
40
0
20
10
% S
% Thr:
0
0
10
0
0
0
10
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
50
0
10
40
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
10
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _