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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6A
All Species:
5.45
Human Site:
T470
Identified Species:
13.33
UniProt:
O15550
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15550
NP_066963.2
1401
154177
T470
Q
A
H
S
W
C
L
T
P
Q
K
L
Q
H
L
Chimpanzee
Pan troglodytes
Q6B4Z3
1079
118013
L191
L
K
H
F
Q
L
A
L
I
D
C
N
P
C
T
Rhesus Macaque
Macaca mulatta
XP_001098278
1273
140201
T385
Q
Q
H
Q
M
R
P
T
G
V
A
Q
V
R
S
Dog
Lupus familis
XP_850658
1401
154200
T470
Q
A
H
S
W
C
L
T
P
Q
K
L
Q
H
L
Cat
Felis silvestris
Mouse
Mus musculus
O70546
1401
154336
Q472
H
S
W
C
L
T
P
Q
K
L
Q
H
L
E
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
N456
H
L
E
Q
L
R
A
N
R
N
N
L
N
P
A
Chicken
Gallus gallus
XP_416762
1384
152840
R464
L
Q
H
L
E
Q
L
R
A
N
R
N
N
L
N
Frog
Xenopus laevis
NP_001086774
1455
160368
L472
I
S
Q
Q
S
L
P
L
H
M
I
P
S
S
Q
Zebra Danio
Brachydanio rerio
XP_697746
1390
152664
L472
L
T
P
Q
K
L
Q
L
L
E
Q
L
R
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
M455
A
G
T
P
T
S
T
M
L
H
G
L
T
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63
90.7
99
N.A.
97.3
N.A.
N.A.
91.2
92
84.2
75.5
N.A.
N.A.
N.A.
N.A.
34.2
Protein Similarity:
100
67.8
90.7
99.4
N.A.
98.2
N.A.
N.A.
93.9
95
89.3
82.9
N.A.
N.A.
N.A.
N.A.
48.1
P-Site Identity:
100
6.6
20
100
N.A.
0
N.A.
N.A.
6.6
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
20
100
N.A.
13.3
N.A.
N.A.
6.6
20
6.6
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
0
0
20
0
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
10
0
20
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
10
% G
% His:
20
0
50
0
0
0
0
0
10
10
0
10
0
20
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
10
0
20
0
0
0
0
% K
% Leu:
30
10
0
10
20
30
30
30
20
10
0
50
10
10
20
% L
% Met:
0
0
0
0
10
0
0
10
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
20
10
20
20
10
20
% N
% Pro:
0
0
10
10
0
0
30
0
20
0
0
10
10
20
0
% P
% Gln:
30
20
10
40
10
10
10
10
0
20
20
10
20
0
20
% Q
% Arg:
0
0
0
0
0
20
0
10
10
0
10
0
10
10
0
% R
% Ser:
0
20
0
20
10
10
0
0
0
0
0
0
10
10
10
% S
% Thr:
0
10
10
0
10
10
10
30
0
0
0
0
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
10
0
20
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _