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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6A
All Species:
18.48
Human Site:
S418
Identified Species:
45.19
UniProt:
O15550
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15550
NP_066963.2
1401
154177
S418
N
K
T
K
L
L
P
S
I
E
E
A
W
S
L
Chimpanzee
Pan troglodytes
Q6B4Z3
1079
118013
Y139
G
L
G
L
V
Y
F
Y
Y
N
A
F
H
W
A
Rhesus Macaque
Macaca mulatta
XP_001098278
1273
140201
Q333
A
V
S
H
P
P
V
Q
Q
Q
A
H
S
W
C
Dog
Lupus familis
XP_850658
1401
154200
S418
N
K
T
K
L
L
P
S
I
E
E
A
W
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O70546
1401
154336
S420
N
K
T
K
L
L
P
S
I
E
E
A
W
S
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
L404
S
L
P
I
P
A
E
L
T
S
R
Q
G
A
M
Chicken
Gallus gallus
XP_416762
1384
152840
A412
A
W
S
L
P
I
P
A
E
L
T
S
R
Q
G
Frog
Xenopus laevis
NP_001086774
1455
160368
S420
N
K
T
K
L
L
P
S
I
E
E
A
W
S
L
Zebra Danio
Brachydanio rerio
XP_697746
1390
152664
S420
S
K
S
K
M
L
P
S
I
E
E
A
W
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
V403
L
T
P
E
Q
Q
I
V
L
Q
Q
F
Q
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63
90.7
99
N.A.
97.3
N.A.
N.A.
91.2
92
84.2
75.5
N.A.
N.A.
N.A.
N.A.
34.2
Protein Similarity:
100
67.8
90.7
99.4
N.A.
98.2
N.A.
N.A.
93.9
95
89.3
82.9
N.A.
N.A.
N.A.
N.A.
48.1
P-Site Identity:
100
0
0
100
N.A.
100
N.A.
N.A.
0
6.6
100
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
13.3
100
N.A.
100
N.A.
N.A.
20
33.3
100
100
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
10
0
10
0
0
20
50
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
10
0
10
50
50
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
20
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
10
10
0
% H
% Ile:
0
0
0
10
0
10
10
0
50
0
0
0
0
0
0
% I
% Lys:
0
50
0
50
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
20
0
20
40
50
0
10
10
10
0
0
0
0
50
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
40
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
0
0
20
0
30
10
60
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
10
10
20
10
10
10
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% R
% Ser:
20
0
30
0
0
0
0
50
0
10
0
10
10
50
0
% S
% Thr:
0
10
40
0
0
0
0
0
10
0
10
0
0
0
0
% T
% Val:
0
10
0
0
10
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
50
20
0
% W
% Tyr:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _