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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF113A All Species: 22.42
Human Site: S84 Identified Species: 30.83
UniProt: O15541 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15541 NP_008909.1 343 38787 S84 K A A Y G D L S S E E E E E N
Chimpanzee Pan troglodytes XP_529135 343 38768 S84 K A A Y G D L S S E E E E E N
Rhesus Macaque Macaca mulatta XP_001083433 344 38832 S84 K A A Y G D L S S E E E E E N
Dog Lupus familis XP_538154 348 39406 E89 G D L S S E E E E E K E E E N
Cat Felis silvestris
Mouse Mus musculus NP_079801 337 38041 S84 K G A Y C D L S S E E E E K A
Rat Rattus norvegicus NP_001004445 337 38010 S84 K G A Y C D L S S E E E E K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509909 347 38316 G88 E R A R R T G G A S S G D E E
Chicken Gallus gallus NP_001004396 328 37759 L72 K E R P S Y A L S S S D D D D
Frog Xenopus laevis NP_001087087 319 36679 S69 D C D D Y K A S S I E E E E K
Zebra Danio Brachydanio rerio NP_001004536 321 36768 S71 K V E R E A V S S S E S E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650865 357 39775 D82 R Q A G G V G D D G S S S A S
Honey Bee Apis mellifera XP_001121039 282 32433 N32 K D Q Q K K I N N D S S E E E
Nematode Worm Caenorhab. elegans O17917 384 43409 H78 Q D I A V A T H S F A A S G D
Sea Urchin Strong. purpuratus XP_780983 697 77998 M435 L S E K Q D V M Y S E S S E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX84 343 38691 P82 K L Y F S S G P S K S S T T T
Baker's Yeast Sacchar. cerevisiae P53769 259 29722 K9 F R K R L V N K S S S D E K N
Red Bread Mold Neurospora crassa Q7SDY3 405 44422 T103 A S T N S G V T K E E Q I R S
Conservation
Percent
Protein Identity: 100 99.7 97.6 93.6 N.A. 89.5 88.9 N.A. 72.3 74.3 68.8 69.3 N.A. 52.6 53.6 38.7 30.4
Protein Similarity: 100 100 98.2 94.2 N.A. 92.7 92.4 N.A. 82.4 83.6 80.1 79.3 N.A. 66.3 63.8 54.6 38.8
P-Site Identity: 100 100 100 33.3 N.A. 73.3 73.3 N.A. 13.3 13.3 40 40 N.A. 13.3 20 6.6 20
P-Site Similarity: 100 100 100 46.6 N.A. 80 80 N.A. 33.3 40 40 46.6 N.A. 26.6 46.6 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. 37.6 27.9 30.6
Protein Similarity: N.A. N.A. N.A. 54.8 47.2 44.2
P-Site Identity: N.A. N.A. N.A. 13.3 20 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 18 42 6 0 12 12 0 6 0 6 6 0 6 12 % A
% Cys: 0 6 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 18 6 6 0 36 0 6 6 6 0 12 12 6 12 % D
% Glu: 6 6 12 0 6 6 6 6 6 42 53 42 59 53 24 % E
% Phe: 6 0 0 6 0 0 0 0 0 6 0 0 0 0 0 % F
% Gly: 6 12 0 6 24 6 18 6 0 6 0 6 0 6 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 0 0 6 0 0 0 6 0 0 6 0 0 6 0 0 % I
% Lys: 53 0 6 6 6 12 0 6 6 6 6 0 0 18 6 % K
% Leu: 6 6 6 0 6 0 30 6 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 0 0 6 6 6 0 0 0 0 0 30 % N
% Pro: 0 0 0 6 0 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 6 6 6 6 6 0 0 0 0 0 0 6 0 0 0 % Q
% Arg: 6 12 6 18 6 0 0 0 0 0 0 0 0 6 0 % R
% Ser: 0 12 0 6 24 6 0 42 65 30 36 30 18 0 12 % S
% Thr: 0 0 6 0 0 6 6 6 0 0 0 0 6 6 6 % T
% Val: 0 6 0 0 6 12 18 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 30 6 6 0 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _