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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUPL2
All Species:
32.12
Human Site:
Y174
Identified Species:
70.67
UniProt:
O15504
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15504
NP_031368.1
423
44872
Y174
T
S
N
N
L
Q
S
Y
L
N
S
V
Q
R
L
Chimpanzee
Pan troglodytes
XP_527687
423
44882
Y174
T
S
N
N
L
Q
S
Y
L
N
S
V
Q
H
L
Rhesus Macaque
Macaca mulatta
XP_001100395
423
44798
Y174
T
S
N
N
L
Q
S
Y
L
N
S
V
Q
H
L
Dog
Lupus familis
XP_853844
537
57007
Y289
T
S
N
N
L
Q
S
Y
L
N
S
L
Q
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIC2
420
44319
Y174
T
S
N
N
L
Q
S
Y
L
N
S
V
Q
Q
L
Rat
Rattus norvegicus
NP_001102687
418
44055
Y174
T
S
N
N
L
Q
S
Y
L
N
S
V
Q
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513740
388
40943
F151
A
N
N
D
L
Q
S
F
L
N
L
V
Q
Q
F
Chicken
Gallus gallus
Q5ZI22
413
42299
Y171
A
N
N
N
T
E
N
Y
I
N
S
V
N
Q
L
Frog
Xenopus laevis
Q5XGN1
491
51686
Y207
A
E
G
N
P
L
K
Y
I
N
A
V
Q
Q
L
Zebra Danio
Brachydanio rerio
Q6P0U9
414
42562
Y162
A
S
G
D
I
Q
P
Y
I
N
S
V
Q
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791728
436
44592
W186
I
L
Y
D
M
E
E
W
E
K
G
K
M
W
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.9
64.4
N.A.
77
77.5
N.A.
52.9
44.6
38.7
39.7
N.A.
N.A.
N.A.
N.A.
20.8
Protein Similarity:
100
99.5
97.6
70.5
N.A.
83.4
83.9
N.A.
63.3
60.5
53.3
55
N.A.
N.A.
N.A.
N.A.
35.3
P-Site Identity:
100
93.3
93.3
86.6
N.A.
93.3
93.3
N.A.
53.3
46.6
40
53.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
80
80
60
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
19
10
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
19
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% H
% Ile:
10
0
0
0
10
0
0
0
28
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% K
% Leu:
0
10
0
0
64
10
0
0
64
0
10
10
0
0
82
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
19
73
73
0
0
10
0
0
91
0
0
10
0
0
% N
% Pro:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
73
0
0
0
0
0
0
82
64
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
64
0
0
0
0
64
0
0
0
73
0
0
0
0
% S
% Thr:
55
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% W
% Tyr:
0
0
10
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _