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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUPL2
All Species:
20
Human Site:
S247
Identified Species:
44
UniProt:
O15504
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15504
NP_031368.1
423
44872
S247
S
D
N
A
Q
N
F
S
F
K
T
N
S
G
F
Chimpanzee
Pan troglodytes
XP_527687
423
44882
S247
S
D
N
A
Q
N
F
S
F
K
T
N
S
G
F
Rhesus Macaque
Macaca mulatta
XP_001100395
423
44798
S247
S
D
N
A
Q
N
F
S
F
K
T
N
S
G
F
Dog
Lupus familis
XP_853844
537
57007
S361
S
T
S
A
Q
N
F
S
F
K
P
S
S
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIC2
420
44319
S247
S
S
T
V
Q
N
F
S
F
K
T
S
P
G
L
Rat
Rattus norvegicus
NP_001102687
418
44055
S247
S
T
T
V
Q
S
F
S
F
K
T
S
P
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513740
388
40943
Q221
S
S
N
T
R
A
D
Q
F
S
F
K
L
G
S
Chicken
Gallus gallus
Q5ZI22
413
42299
K244
G
A
A
S
F
S
F
K
A
N
P
S
V
P
P
Frog
Xenopus laevis
Q5XGN1
491
51686
S314
T
S
A
P
S
F
G
S
G
V
A
A
A
A
A
Zebra Danio
Brachydanio rerio
Q6P0U9
414
42562
F238
A
G
F
G
G
A
G
F
G
S
G
P
Q
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791728
436
44592
Q261
K
L
K
S
R
L
G
Q
L
L
Q
A
S
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.9
64.4
N.A.
77
77.5
N.A.
52.9
44.6
38.7
39.7
N.A.
N.A.
N.A.
N.A.
20.8
Protein Similarity:
100
99.5
97.6
70.5
N.A.
83.4
83.9
N.A.
63.3
60.5
53.3
55
N.A.
N.A.
N.A.
N.A.
35.3
P-Site Identity:
100
100
100
73.3
N.A.
60
53.3
N.A.
26.6
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
66.6
N.A.
33.3
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
37
0
19
0
0
10
0
10
19
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
10
0
10
10
64
10
64
0
10
0
0
0
37
% F
% Gly:
10
10
0
10
10
0
28
0
19
0
10
0
0
64
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
0
0
0
10
0
55
0
10
0
0
0
% K
% Leu:
0
10
0
0
0
10
0
0
10
10
0
0
10
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
37
0
0
46
0
0
0
10
0
28
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
19
10
19
10
10
% P
% Gln:
0
0
0
0
55
0
0
19
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
64
28
10
19
10
19
0
64
0
19
0
37
46
10
19
% S
% Thr:
10
19
19
10
0
0
0
0
0
0
46
0
0
0
0
% T
% Val:
0
0
0
19
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _