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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YKT6 All Species: 36.67
Human Site: Y69 Identified Species: 53.78
UniProt: O15498 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15498 NP_006546.1 198 22418 Y69 Q D Y L C H V Y V R N D S L A
Chimpanzee Pan troglodytes XP_001143818 250 27829 Y69 Q D Y L C H V Y V R N D S L A
Rhesus Macaque Macaca mulatta XP_001092856 326 36094 C70 Q D Y L W H V C V Q N D S L A
Dog Lupus familis XP_532720 169 19159 V41 E Y L C H V Y V R N D S L A G
Cat Felis silvestris
Mouse Mus musculus Q9CQW1 198 22296 Y69 Q E Y L C H V Y V R S D S L A
Rat Rattus norvegicus Q5EGY4 198 22351 Y69 Q E Y L C H V Y V R S D S L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521372 163 18456 V35 E Y F C H G Y V R H D G L A G
Chicken Gallus gallus NP_001107216 198 22405 Y69 Q D Y L C H V Y V R S D G L A
Frog Xenopus laevis Q32N70 198 22594 Y69 Q E Y L C H V Y V R N D S L A
Zebra Danio Brachydanio rerio Q7ZUN8 198 22387 Y69 Q E Y L C H V Y V R N D N L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572423 199 22400 Y70 D A Y M C H V Y V R A D N L A
Honey Bee Apis mellifera XP_624934 200 22741 F70 G D Y M C H V F V R A D N L A
Nematode Worm Caenorhab. elegans NP_498605 201 23132 Y71 N E Y L V H C Y V R N D G L S
Sea Urchin Strong. purpuratus XP_779975 205 23371 M69 K D Y I F H V M C R E S N L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRD6 199 22525 A70 H E E Y K V H A Y N R N G L C
Baker's Yeast Sacchar. cerevisiae P36015 200 22688 Y69 G N Y I G H V Y A R S E G I C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66 50.9 80.8 N.A. 92.9 94.9 N.A. 75.2 86.3 88.8 84.8 N.A. 61.3 58.5 55.7 57
Protein Similarity: 100 69.1 54.9 84.3 N.A. 96.4 97.9 N.A. 77.2 92.9 94.4 90.4 N.A. 77.3 75.5 72.1 74.6
P-Site Identity: 100 100 80 0 N.A. 86.6 86.6 N.A. 0 86.6 93.3 80 N.A. 66.6 66.6 60 46.6
P-Site Similarity: 100 100 86.6 13.3 N.A. 100 100 N.A. 20 93.3 100 93.3 N.A. 80 86.6 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 46.2 47.5 N.A.
Protein Similarity: N.A. N.A. N.A. 61.8 67 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 7 0 13 0 0 13 63 % A
% Cys: 0 0 0 13 57 0 7 7 7 0 0 0 0 0 13 % C
% Asp: 7 38 0 0 0 0 0 0 0 0 13 69 0 0 0 % D
% Glu: 13 38 7 0 0 0 0 0 0 0 7 7 0 0 0 % E
% Phe: 0 0 7 0 7 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 0 7 7 0 0 0 0 0 7 25 0 19 % G
% His: 7 0 0 0 13 82 7 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 57 0 0 0 0 0 0 0 0 13 82 0 % L
% Met: 0 0 0 13 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 0 0 13 38 7 25 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 50 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 75 7 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 25 13 38 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 7 13 75 13 69 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 82 7 0 0 13 63 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _