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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOX3
All Species:
16.36
Human Site:
S433
Identified Species:
40
UniProt:
O15405
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15405
NP_001073899.2
576
63342
S433
S
A
P
S
T
Q
V
S
P
S
V
Q
T
Q
Q
Chimpanzee
Pan troglodytes
XP_001165206
577
63461
S433
S
A
P
S
T
Q
V
S
P
S
V
Q
T
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001085004
541
59537
L471
Q
Q
I
N
Q
Q
Q
L
Q
Q
Q
L
Q
Q
R
Dog
Lupus familis
XP_544407
390
42526
A321
G
E
V
S
K
I
V
A
S
M
W
D
S
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80W03
575
63155
S432
S
A
T
S
T
Q
V
S
P
S
V
Q
T
Q
Q
Rat
Rattus norvegicus
Q99PM1
619
65991
E511
T
V
L
P
P
T
V
E
S
S
P
E
Q
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520125
610
67306
S471
S
P
S
S
T
Q
A
S
P
S
V
Q
T
Q
Q
Chicken
Gallus gallus
XP_414090
578
63685
S436
T
P
S
S
S
Q
V
S
P
S
M
Q
S
Q
Q
Frog
Xenopus laevis
Q6IRR0
594
63660
A439
P
P
R
L
L
Q
M
A
P
A
Q
Q
P
S
I
Zebra Danio
Brachydanio rerio
XP_001922515
597
66026
P452
S
V
S
S
Q
L
S
P
P
M
Q
P
R
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.8
55.5
N.A.
95.1
39.5
N.A.
80.4
89
40.2
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
92.8
58.3
N.A.
96.8
55.5
N.A.
85.9
94.2
57.7
73.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
93.3
13.3
N.A.
80
60
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
93.3
26.6
N.A.
80
86.6
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
0
0
10
20
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
10
10
0
10
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
20
10
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
30
20
10
10
0
0
10
70
0
10
10
10
10
0
% P
% Gln:
10
10
0
0
20
70
10
0
10
10
30
60
20
60
50
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
50
0
30
70
10
0
10
50
20
60
0
0
20
10
10
% S
% Thr:
20
0
10
0
40
10
0
0
0
0
0
0
40
0
0
% T
% Val:
0
20
10
0
0
0
60
0
0
0
40
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _