KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
19.39
Human Site:
Y127
Identified Species:
28.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
Y127
N
S
S
L
L
S
L
Y
R
K
G
N
P
D
S
Chimpanzee
Pan troglodytes
XP_514229
905
100536
Y161
N
S
S
L
L
S
L
Y
R
K
G
N
P
D
S
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
Y127
N
S
S
L
L
S
L
Y
R
K
G
N
P
D
S
Dog
Lupus familis
XP_537239
955
104441
Y200
N
S
S
L
L
S
L
Y
R
K
G
H
P
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
Y126
N
S
S
L
L
S
L
Y
R
R
G
N
S
E
S
Rat
Rattus norvegicus
P46462
806
89330
V108
S
I
Q
P
C
P
D
V
K
Y
G
K
R
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
E55
R
R
Q
E
T
L
Q
E
V
D
G
E
I
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
V108
S
I
Q
P
C
P
D
V
K
Y
G
K
R
V
H
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
V108
S
I
Q
P
C
P
D
V
K
Y
G
K
R
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
G108
S
C
P
D
V
K
Y
G
K
R
V
R
I
L
P
Honey Bee
Apis mellifera
XP_392923
818
90486
R108
N
K
M
E
S
N
S
R
K
A
S
E
P
E
V
Nematode Worm
Caenorhab. elegans
P54812
810
89622
S110
G
D
V
V
S
I
S
S
A
Q
L
E
Y
G
K
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
T110
K
N
R
S
A
A
S
T
P
L
G
G
T
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
L113
Q
R
A
E
Q
S
H
L
R
K
R
N
M
E
R
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
E123
G
Y
N
N
E
E
E
E
K
P
S
L
E
E
E
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
C228
N
P
G
R
I
T
L
C
E
P
V
A
Q
G
I
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
93.3
N.A.
80
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
13.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
13.3
N.A.
20
20
N.A.
26.6
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
0
0
7
7
0
7
0
0
0
% A
% Cys:
0
7
0
0
19
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
19
0
0
7
0
0
0
25
7
% D
% Glu:
0
0
0
19
7
7
7
13
7
0
0
19
7
32
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
7
0
0
0
0
7
0
0
63
7
0
13
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
19
% H
% Ile:
0
19
0
0
7
7
0
0
0
0
0
0
13
13
7
% I
% Lys:
7
7
0
0
0
7
0
0
38
32
0
19
0
0
7
% K
% Leu:
0
0
0
32
32
7
38
7
0
7
7
7
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
44
7
7
7
0
7
0
0
0
0
0
32
0
0
0
% N
% Pro:
0
7
7
19
0
19
0
0
7
13
0
0
32
7
7
% P
% Gln:
7
0
25
0
7
0
7
0
0
7
0
0
7
0
7
% Q
% Arg:
7
13
7
7
0
0
0
7
38
13
7
7
19
0
7
% R
% Ser:
25
32
32
7
13
38
19
7
0
0
13
0
7
0
32
% S
% Thr:
0
0
0
0
7
7
0
7
0
0
0
0
7
0
0
% T
% Val:
0
0
7
7
7
0
0
19
7
0
13
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
32
0
19
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _