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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
20
Human Site:
Y110
Identified Species:
29.33
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
Y110
D
D
S
S
M
E
D
Y
P
D
P
Q
S
A
N
Chimpanzee
Pan troglodytes
XP_514229
905
100536
Y144
D
D
S
S
M
E
D
Y
P
D
P
Q
S
A
N
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
Y110
D
D
S
S
M
E
D
Y
P
D
P
Q
S
A
N
Dog
Lupus familis
XP_537239
955
104441
Y183
S
D
S
N
M
E
D
Y
P
D
P
Q
V
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
Y109
D
D
S
N
M
E
D
Y
P
D
P
Q
S
A
N
Rat
Rattus norvegicus
P46462
806
89330
N91
M
N
R
V
V
R
N
N
L
R
V
R
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
K38
S
L
P
Q
R
E
R
K
K
K
G
R
L
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
N91
M
N
R
V
V
R
N
N
L
R
V
R
L
G
D
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
N91
M
N
R
V
V
R
N
N
L
R
V
R
L
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
V91
V
V
R
N
N
L
C
V
H
L
S
D
V
V
S
Honey Bee
Apis mellifera
XP_392923
818
90486
L91
G
N
S
S
D
K
E
L
I
D
I
S
S
D
D
Nematode Worm
Caenorhab. elegans
P54812
810
89622
V93
D
K
I
K
M
N
K
V
V
R
N
N
L
R
S
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
Y93
N
S
T
L
S
N
L
Y
K
K
G
T
P
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
R96
A
S
Q
R
K
K
Q
R
R
V
D
E
K
E
E
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
S106
M
L
K
D
V
I
E
S
E
L
E
E
F
G
S
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
P211
D
F
F
P
L
P
L
P
P
H
P
V
T
H
Q
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
80
N.A.
93.3
0
N.A.
6.6
N.A.
0
0
N.A.
0
26.6
13.3
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
33.3
N.A.
13.3
N.A.
33.3
33.3
N.A.
13.3
53.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
0
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
0
0
32
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
38
32
0
7
7
0
32
0
0
38
7
7
0
7
25
% D
% Glu:
0
0
0
0
0
38
13
0
7
0
7
13
0
7
7
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
13
0
0
25
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
0
0
7
0
% H
% Ile:
0
0
7
0
0
7
0
0
7
0
7
0
0
0
0
% I
% Lys:
0
7
7
7
7
13
7
7
13
13
0
0
7
7
0
% K
% Leu:
0
13
0
7
7
7
13
7
19
13
0
0
32
0
0
% L
% Met:
25
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
25
0
19
7
13
19
19
0
0
7
7
0
0
38
% N
% Pro:
0
0
7
7
0
7
0
7
38
0
38
0
7
0
0
% P
% Gln:
0
0
7
7
0
0
7
0
0
0
0
32
0
0
7
% Q
% Arg:
0
0
25
7
7
19
7
7
7
25
0
25
0
7
7
% R
% Ser:
13
13
38
25
7
0
0
7
0
0
7
7
32
0
19
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
7
7
7
0
% T
% Val:
7
7
0
19
25
0
0
13
7
7
19
7
13
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _