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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NVL All Species: 22.73
Human Site: T410 Identified Species: 33.33
UniProt: O15381 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15381 NP_002524.2 856 95051 T410 R V L V I G A T N R P D S L D
Chimpanzee Pan troglodytes XP_514229 905 100536 T444 R V L V I G A T N R P D S L D
Rhesus Macaque Macaca mulatta XP_001096627 856 94931 T410 R V L V I G A T N R P D S L D
Dog Lupus familis XP_537239 955 104441 T477 R V L V I G A T N R P D S L D
Cat Felis silvestris
Mouse Mus musculus Q9DBY8 855 94457 T409 R V L V I G A T N R P D S L D
Rat Rattus norvegicus P46462 806 89330 A356 R P N S I D P A L R R F G R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512479 677 74669 A303 C R E A A M C A V N R V L I N
Chicken Gallus gallus
Frog Xenopus laevis P23787 805 89193 A356 R P N S I D P A L R R F G R F
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 A356 R P N S I D P A L R R F G R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 R356 S I D P A L R R F G R F D R E
Honey Bee Apis mellifera XP_392923 818 90486 T368 R V L V L G A T N R P D S L D
Nematode Worm Caenorhab. elegans P54812 810 89622 I358 A T N R P N S I D G A L R R F
Sea Urchin Strong. purpuratus XP_785648 742 81148 E358 K R E T A Q R E M E R R I V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SS94 820 89986 F379 A P D S S A G F V L V I G A T
Baker's Yeast Sacchar. cerevisiae Q07844 837 93051 M390 R L H I L K K M S D N L K I D
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 N691 R I P G T I S N S W Q Y Y L G
Conservation
Percent
Protein Identity: 100 92.3 97.6 77.2 N.A. 87.8 35.9 N.A. 65.7 N.A. 35.9 35.7 N.A. 33.8 49.2 35.8 48.1
Protein Similarity: 100 93.1 98.5 83.1 N.A. 93.2 54.2 N.A. 72.1 N.A. 53.3 54.2 N.A. 54.2 65.1 54.2 60.5
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 0 N.A. 20 20 N.A. 0 93.3 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 13.3 N.A. 20 20 N.A. 13.3 100 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 37.8 42.2 22.9
Protein Similarity: N.A. N.A. N.A. 57 61.5 38.1
P-Site Identity: N.A. N.A. N.A. 0 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 0 46.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 7 19 7 38 25 0 0 7 0 0 7 7 % A
% Cys: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 19 0 0 7 7 0 38 7 0 44 % D
% Glu: 0 0 13 0 0 0 0 7 0 7 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 7 7 0 0 25 0 0 25 % F
% Gly: 0 0 0 7 0 38 7 0 0 13 0 0 25 0 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 0 7 50 7 0 7 0 0 0 7 7 13 0 % I
% Lys: 7 0 0 0 0 7 7 0 0 0 0 0 7 0 0 % K
% Leu: 0 7 38 0 13 7 0 0 19 7 0 13 7 44 0 % L
% Met: 0 0 0 0 0 7 0 7 7 0 0 0 0 0 0 % M
% Asn: 0 0 25 0 0 7 0 7 38 7 7 0 0 0 7 % N
% Pro: 0 25 7 7 7 0 19 0 0 0 38 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % Q
% Arg: 69 13 0 7 0 0 13 7 0 57 38 7 7 32 0 % R
% Ser: 7 0 0 25 7 0 13 0 13 0 0 0 38 0 0 % S
% Thr: 0 7 0 7 7 0 0 38 0 0 0 0 0 0 7 % T
% Val: 0 38 0 38 0 0 0 0 13 0 7 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _