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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
19.39
Human Site:
T273
Identified Species:
28.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
T273
D
V
G
G
N
D
M
T
L
K
E
V
C
K
M
Chimpanzee
Pan troglodytes
XP_514229
905
100536
T307
D
V
G
G
N
D
M
T
L
K
E
V
C
K
M
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
T273
D
V
G
G
N
D
M
T
L
K
E
V
C
K
M
Dog
Lupus familis
XP_537239
955
104441
T340
D
V
G
G
N
D
A
T
L
K
E
V
C
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
T272
D
V
G
G
N
D
A
T
L
K
E
V
C
K
M
Rat
Rattus norvegicus
P46462
806
89330
P237
F
K
A
I
G
V
K
P
P
R
G
I
L
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
I184
C
I
L
F
I
D
E
I
D
A
I
T
P
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
P237
F
K
A
I
G
V
K
P
P
R
G
I
L
L
Y
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
P237
F
K
A
I
G
V
K
P
P
R
G
I
L
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
G237
I
G
V
K
P
P
R
G
I
L
M
Y
G
P
P
Honey Bee
Apis mellifera
XP_392923
818
90486
L238
V
L
K
T
V
C
K
L
L
A
H
M
K
H
P
Nematode Worm
Caenorhab. elegans
P54812
810
89622
G239
P
Q
L
F
K
A
I
G
V
K
P
P
R
G
I
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
S239
K
V
I
E
P
Q
R
S
T
S
T
F
A
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
L242
F
G
G
I
K
K
I
L
D
E
L
E
M
N
V
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
S254
P
P
G
C
G
K
T
S
I
A
N
A
L
A
G
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
D409
E
E
A
C
I
Y
V
D
M
R
D
L
T
R
V
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
13.3
N.A.
0
0
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
20
N.A.
13.3
13.3
N.A.
6.6
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
7
13
0
0
19
0
7
7
7
0
% A
% Cys:
7
0
0
13
0
7
0
0
0
0
0
0
32
0
0
% C
% Asp:
32
0
0
0
0
38
0
7
13
0
7
0
0
7
0
% D
% Glu:
7
7
0
7
0
0
7
0
0
7
32
7
0
0
0
% E
% Phe:
25
0
0
13
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
13
44
32
25
0
0
13
0
0
19
0
7
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
7
7
7
25
13
0
13
7
13
0
7
19
0
0
7
% I
% Lys:
7
19
7
7
13
13
25
0
0
38
0
0
7
38
0
% K
% Leu:
0
7
13
0
0
0
0
13
38
7
7
7
25
19
0
% L
% Met:
0
0
0
0
0
0
19
0
7
0
7
7
7
0
38
% M
% Asn:
0
0
0
0
32
0
0
0
0
0
7
0
0
7
0
% N
% Pro:
13
7
0
0
13
7
0
19
19
0
7
7
7
7
13
% P
% Gln:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
13
0
0
25
0
0
7
7
7
% R
% Ser:
0
0
0
0
0
0
0
13
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
0
7
32
7
0
7
7
7
0
0
% T
% Val:
7
38
7
0
7
19
7
0
7
0
0
32
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _