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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
20.91
Human Site:
T157
Identified Species:
30.67
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
T157
T
P
R
I
S
S
K
T
G
S
I
P
L
K
T
Chimpanzee
Pan troglodytes
XP_514229
905
100536
T191
T
P
Q
I
S
S
K
T
G
S
I
P
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
T157
T
P
Q
I
S
S
K
T
G
S
V
P
L
K
T
Dog
Lupus familis
XP_537239
955
104441
T230
V
P
R
M
P
S
G
T
G
S
G
P
L
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
T156
T
P
L
L
T
S
K
T
G
S
V
P
L
K
T
Rat
Rattus norvegicus
P46462
806
89330
Y138
F
E
V
Y
L
K
P
Y
F
L
E
A
Y
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
V85
S
A
L
K
F
E
D
V
G
G
N
D
A
T
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
Y138
F
E
V
Y
L
K
P
Y
F
L
E
A
Y
R
P
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
Y138
F
E
V
Y
L
K
P
Y
F
L
E
A
Y
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
E138
Y
L
K
P
Y
F
L
E
A
Y
R
P
I
H
M
Honey Bee
Apis mellifera
XP_392923
818
90486
I138
K
T
T
H
A
K
E
I
E
Q
L
R
R
P
S
Nematode Worm
Caenorhab. elegans
P54812
810
89622
L140
G
N
L
F
D
V
F
L
R
P
Y
F
T
D
A
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
T140
S
V
E
M
S
N
V
T
L
D
L
A
G
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
D143
G
D
V
S
T
S
E
D
A
V
Y
G
E
K
L
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
W153
N
K
R
I
T
S
T
W
S
K
S
G
S
V
S
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
S258
K
T
K
R
S
S
A
S
G
Q
Q
Q
G
R
K
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
93.3
86.6
60
N.A.
73.3
0
N.A.
6.6
N.A.
0
0
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
6.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
20
26.6
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
7
0
13
0
0
25
7
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
0
7
7
0
7
0
7
0
7
0
% D
% Glu:
0
19
7
0
0
7
13
7
7
0
19
0
7
0
0
% E
% Phe:
19
0
0
7
7
7
7
0
19
0
0
7
0
0
0
% F
% Gly:
13
0
0
0
0
0
7
0
44
7
7
13
13
0
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
25
0
0
0
7
0
0
13
0
7
0
0
% I
% Lys:
13
7
13
7
0
25
25
0
0
7
0
0
0
38
7
% K
% Leu:
0
7
19
7
19
0
7
7
7
19
13
0
32
0
13
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
32
0
7
7
0
19
0
0
7
0
38
0
7
19
% P
% Gln:
0
0
13
0
0
0
0
0
0
13
7
7
0
0
0
% Q
% Arg:
0
0
19
7
0
0
0
0
7
0
7
7
7
25
0
% R
% Ser:
13
0
0
7
32
50
0
7
7
32
7
0
7
0
13
% S
% Thr:
25
13
7
0
19
0
7
38
0
0
0
0
7
7
25
% T
% Val:
7
7
25
0
0
7
7
7
0
7
13
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
19
7
0
0
19
0
7
13
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _