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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
20.3
Human Site:
T138
Identified Species:
29.78
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
T138
N
P
D
S
V
S
N
T
P
E
M
E
Q
R
E
Chimpanzee
Pan troglodytes
XP_514229
905
100536
T172
N
P
D
S
V
S
N
T
P
E
M
E
Q
R
E
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
T138
N
P
D
S
V
S
N
T
P
E
M
E
Q
R
E
Dog
Lupus familis
XP_537239
955
104441
T211
H
P
D
S
V
T
S
T
P
E
M
E
P
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
T137
N
S
E
S
V
S
T
T
P
K
W
G
Q
R
E
Rat
Rattus norvegicus
P46462
806
89330
I119
K
R
I
H
V
L
P
I
D
D
T
V
E
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
K66
E
I
E
D
V
L
R
K
K
A
K
S
T
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
I119
K
R
V
H
V
L
P
I
D
D
T
V
E
G
I
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
I119
K
R
I
H
V
L
P
I
D
D
T
V
E
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
S119
R
I
L
P
I
D
E
S
T
E
G
V
T
G
N
Honey Bee
Apis mellifera
XP_392923
818
90486
L119
E
P
E
V
V
E
N
L
Q
Q
K
P
G
P
S
Nematode Worm
Caenorhab. elegans
P54812
810
89622
V121
E
Y
G
K
R
V
H
V
L
P
I
D
D
T
I
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
M121
G
T
P
Q
A
T
P
M
P
S
D
S
D
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
S124
N
M
E
R
S
V
S
S
S
P
S
S
S
S
S
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
K134
L
E
E
E
L
A
K
K
N
M
M
I
E
R
D
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
T239
A
Q
G
I
L
A
P
T
T
K
I
I
V
S
R
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
73.3
N.A.
60
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
6.6
20
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
20
N.A.
13.3
N.A.
20
20
N.A.
20
33.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
13
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
7
0
7
0
0
19
19
7
7
13
0
13
% D
% Glu:
19
7
32
7
0
7
7
0
0
32
0
25
25
7
32
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
13
0
0
0
0
0
0
0
7
7
7
32
0
% G
% His:
7
0
0
19
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
13
7
7
0
0
19
0
0
13
13
0
0
25
% I
% Lys:
19
0
0
7
0
0
7
13
7
13
13
0
0
0
0
% K
% Leu:
7
0
7
0
13
25
0
7
7
0
0
0
0
0
7
% L
% Met:
0
7
0
0
0
0
0
7
0
7
32
0
0
0
0
% M
% Asn:
32
0
0
0
0
0
25
0
7
0
0
0
0
0
7
% N
% Pro:
0
32
7
7
0
0
32
0
38
13
0
7
7
7
0
% P
% Gln:
0
7
0
7
0
0
0
0
7
7
0
0
25
0
0
% Q
% Arg:
7
19
0
7
7
0
7
0
0
0
0
0
0
38
7
% R
% Ser:
0
7
0
32
7
25
13
13
7
7
7
19
7
13
13
% S
% Thr:
0
7
0
0
0
13
7
38
13
0
19
0
13
7
0
% T
% Val:
0
0
7
7
63
13
0
7
0
0
0
25
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _