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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
10.3
Human Site:
S228
Identified Species:
15.11
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S228
G
K
L
K
N
K
G
S
K
R
K
K
E
D
L
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S262
G
K
L
K
N
K
G
S
K
R
K
K
E
D
L
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S228
G
R
L
K
N
K
G
S
K
R
K
K
E
D
L
Dog
Lupus familis
XP_537239
955
104441
D301
K
G
N
K
R
K
K
D
V
Q
E
A
D
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
N227
G
R
A
K
G
K
G
N
K
R
K
T
E
N
L
Rat
Rattus norvegicus
P46462
806
89330
C209
G
Y
D
D
I
G
G
C
R
K
Q
L
A
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
V156
A
T
E
I
V
S
G
V
S
G
E
S
E
Q
K
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
C209
G
Y
D
D
I
G
G
C
R
K
Q
L
A
Q
I
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
V209
G
Y
D
D
I
G
G
V
R
K
Q
L
A
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
Q209
D
I
G
G
C
R
K
Q
L
A
Q
I
K
E
M
Honey Bee
Apis mellifera
XP_392923
818
90486
K209
S
D
I
R
G
N
D
K
T
K
R
I
P
I
S
Nematode Worm
Caenorhab. elegans
P54812
810
89622
L211
N
E
V
G
Y
D
D
L
G
G
V
R
K
Q
L
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
E211
A
K
G
E
D
G
V
E
A
S
A
K
K
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
S214
A
K
V
S
L
S
L
S
G
A
T
G
N
G
D
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
P224
L
M
E
L
I
G
L
P
I
L
H
P
E
I
F
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
T329
I
I
S
L
Q
V
P
T
L
P
T
T
V
T
G
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
93.3
13.3
N.A.
60
13.3
N.A.
13.3
N.A.
13.3
13.3
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
80
40
N.A.
20
N.A.
40
40
N.A.
33.3
26.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
7
0
0
0
0
0
7
13
7
7
19
0
0
% A
% Cys:
0
0
0
0
7
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
7
7
19
19
7
7
13
7
0
0
0
0
7
19
7
% D
% Glu:
0
7
13
7
0
0
0
7
0
0
13
0
38
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
44
7
13
13
13
32
50
0
13
13
0
7
0
13
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
13
7
7
25
0
0
0
7
0
0
13
0
13
19
% I
% Lys:
7
25
0
32
0
32
13
7
25
25
25
25
19
7
7
% K
% Leu:
7
0
19
13
7
0
13
7
13
7
0
19
0
0
32
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
0
7
0
19
7
0
7
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
7
7
0
7
0
7
7
0
7
% P
% Gln:
0
0
0
0
7
0
0
7
0
7
25
0
0
32
0
% Q
% Arg:
0
13
0
7
7
7
0
0
19
25
7
7
0
0
0
% R
% Ser:
7
0
7
7
0
13
0
25
7
7
0
7
0
0
7
% S
% Thr:
0
7
0
0
0
0
0
7
7
0
13
13
0
7
0
% T
% Val:
0
0
13
0
7
7
7
13
7
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _