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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
16.06
Human Site:
S210
Identified Species:
23.56
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S210
E
I
Q
D
S
K
D
S
S
L
L
E
S
D
M
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S244
E
I
Q
D
S
K
D
S
S
L
L
E
S
D
M
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S210
E
I
Q
G
S
K
D
S
S
L
L
E
S
D
M
Dog
Lupus familis
XP_537239
955
104441
S283
K
D
A
S
L
L
E
S
N
E
K
R
K
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S209
E
I
Q
I
L
K
D
S
S
L
L
E
S
D
K
Rat
Rattus norvegicus
P46462
806
89330
R191
C
E
G
E
P
I
K
R
E
D
E
E
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
G138
L
L
A
Q
A
I
A
G
E
L
D
L
P
I
L
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
R191
C
E
G
E
P
I
K
R
E
D
E
E
E
S
L
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
R191
C
E
G
E
P
I
K
R
E
D
E
E
E
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
E191
D
P
I
K
R
E
E
E
E
E
S
L
N
A
V
Honey Bee
Apis mellifera
XP_392923
818
90486
G191
T
F
V
R
K
T
K
G
I
P
I
S
D
P
K
Nematode Worm
Caenorhab. elegans
P54812
810
89622
P193
V
I
H
Y
E
G
D
P
I
K
R
E
E
E
E
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
K193
Y
I
S
K
T
P
S
K
V
A
R
T
P
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
S196
T
V
S
N
K
G
R
S
K
L
A
T
M
G
A
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
S206
P
P
N
S
S
L
K
S
L
G
G
M
D
D
V
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
E311
E
P
Q
A
G
E
D
E
D
N
L
S
D
D
S
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
93.3
6.6
N.A.
80
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
0
20
6.6
P-Site Similarity:
100
100
93.3
26.6
N.A.
80
20
N.A.
26.6
N.A.
20
20
N.A.
33.3
6.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
7
7
0
7
0
0
7
7
0
0
7
7
% A
% Cys:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
13
0
0
38
0
7
19
7
0
19
38
0
% D
% Glu:
32
19
0
19
7
13
13
13
32
13
19
50
25
7
7
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
19
7
7
13
0
13
0
7
7
0
0
13
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
38
7
7
0
25
0
0
13
0
7
0
0
7
0
% I
% Lys:
7
0
0
13
13
25
32
7
7
7
7
0
7
0
13
% K
% Leu:
7
7
0
0
13
13
0
0
7
38
32
13
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
19
% M
% Asn:
0
0
7
7
0
0
0
0
7
7
0
0
7
0
0
% N
% Pro:
7
19
0
0
19
7
0
7
0
7
0
0
13
7
0
% P
% Gln:
0
0
32
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
7
0
7
19
0
0
13
7
0
7
13
% R
% Ser:
0
0
13
13
25
0
7
44
25
0
7
13
25
19
7
% S
% Thr:
13
0
0
0
7
7
0
0
0
0
0
13
0
0
0
% T
% Val:
7
7
7
0
0
0
0
0
7
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _