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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
19.39
Human Site:
S149
Identified Species:
28.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S149
E
Q
R
E
T
T
S
S
T
P
R
I
S
S
K
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S183
E
Q
R
E
T
T
S
S
T
P
Q
I
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S149
E
Q
R
E
T
T
S
S
T
P
Q
I
S
S
K
Dog
Lupus familis
XP_537239
955
104441
S222
E
P
R
E
T
T
V
S
V
P
R
M
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S148
G
Q
R
E
A
T
T
S
T
P
L
L
T
S
K
Rat
Rattus norvegicus
P46462
806
89330
L130
V
E
G
I
T
G
N
L
F
E
V
Y
L
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
I77
S
T
G
L
Q
L
Q
I
S
A
L
K
F
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
L130
V
E
G
I
T
G
N
L
F
E
V
Y
L
K
P
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L130
V
E
G
I
T
G
N
L
F
E
V
Y
L
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
I130
V
T
G
N
L
F
E
I
Y
L
K
P
Y
F
L
Honey Bee
Apis mellifera
XP_392923
818
90486
E130
P
G
P
S
S
S
T
E
K
T
T
H
A
K
E
Nematode Worm
Caenorhab. elegans
P54812
810
89622
T132
D
D
T
I
E
G
L
T
G
N
L
F
D
V
F
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
D132
S
D
E
D
D
D
R
D
S
V
E
M
S
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
S135
S
S
S
S
S
E
D
S
G
D
V
S
T
S
E
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
M145
I
E
R
D
T
N
E
M
N
K
R
I
T
S
T
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
S250
I
V
S
R
V
R
T
S
K
T
K
R
S
S
A
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
93.3
93.3
60
N.A.
60
6.6
N.A.
0
N.A.
6.6
6.6
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
100
66.6
N.A.
80
20
N.A.
6.6
N.A.
20
20
N.A.
6.6
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
7
0
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
13
0
13
7
7
7
7
0
7
0
0
7
0
7
% D
% Glu:
25
25
7
32
7
7
13
7
0
19
7
0
0
7
13
% E
% Phe:
0
0
0
0
0
7
0
0
19
0
0
7
7
7
7
% F
% Gly:
7
7
32
0
0
25
0
0
13
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
13
0
0
25
0
0
0
13
0
0
0
25
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
13
7
13
7
0
25
25
% K
% Leu:
0
0
0
7
7
7
7
19
0
7
19
7
19
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
7
0
7
19
0
7
7
0
0
0
7
0
% N
% Pro:
7
7
7
0
0
0
0
0
0
32
0
7
7
0
19
% P
% Gln:
0
25
0
0
7
0
7
0
0
0
13
0
0
0
0
% Q
% Arg:
0
0
38
7
0
7
7
0
0
0
19
7
0
0
0
% R
% Ser:
19
7
13
13
13
7
19
44
13
0
0
7
32
50
0
% S
% Thr:
0
13
7
0
50
32
19
7
25
13
7
0
19
0
7
% T
% Val:
25
7
0
0
7
0
7
0
7
7
25
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
19
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _