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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NVL
All Species:
16.67
Human Site:
S115
Identified Species:
24.44
UniProt:
O15381
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15381
NP_002524.2
856
95051
S115
E
D
Y
P
D
P
Q
S
A
N
H
M
N
S
S
Chimpanzee
Pan troglodytes
XP_514229
905
100536
S149
E
D
Y
P
D
P
Q
S
A
N
H
M
N
S
S
Rhesus Macaque
Macaca mulatta
XP_001096627
856
94931
S115
E
D
Y
P
D
P
Q
S
A
N
H
M
N
S
S
Dog
Lupus familis
XP_537239
955
104441
V188
E
D
Y
P
D
P
Q
V
A
N
H
M
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBY8
855
94457
S114
E
D
Y
P
D
P
Q
S
A
N
P
M
N
S
S
Rat
Rattus norvegicus
P46462
806
89330
L96
R
N
N
L
R
V
R
L
G
D
V
I
S
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512479
677
74669
L43
E
R
K
K
K
G
R
L
K
R
G
K
R
R
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
P23787
805
89193
L96
R
N
N
L
R
V
R
L
G
D
V
I
S
I
Q
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
L96
R
N
N
L
R
V
R
L
G
D
V
I
S
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
V96
L
C
V
H
L
S
D
V
V
S
V
Q
S
C
P
Honey Bee
Apis mellifera
XP_392923
818
90486
S96
K
E
L
I
D
I
S
S
D
D
D
V
N
K
M
Nematode Worm
Caenorhab. elegans
P54812
810
89622
L98
N
K
V
V
R
N
N
L
R
S
R
L
G
D
V
Sea Urchin
Strong. purpuratus
XP_785648
742
81148
P98
N
L
Y
K
K
G
T
P
T
N
T
P
K
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SS94
820
89986
K101
K
Q
R
R
V
D
E
K
E
E
K
L
Q
R
A
Baker's Yeast
Sacchar. cerevisiae
Q07844
837
93051
F111
I
E
S
E
L
E
E
F
G
S
Y
P
G
Y
N
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
T216
P
L
P
P
H
P
V
T
H
Q
P
P
N
P
G
Conservation
Percent
Protein Identity:
100
92.3
97.6
77.2
N.A.
87.8
35.9
N.A.
65.7
N.A.
35.9
35.7
N.A.
33.8
49.2
35.8
48.1
Protein Similarity:
100
93.1
98.5
83.1
N.A.
93.2
54.2
N.A.
72.1
N.A.
53.3
54.2
N.A.
54.2
65.1
54.2
60.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
6.6
N.A.
0
0
N.A.
0
20
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
13.3
N.A.
33.3
33.3
N.A.
13.3
46.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
42.2
22.9
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
38.1
P-Site Identity:
N.A.
N.A.
N.A.
0
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
32
0
0
0
0
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
32
0
0
38
7
7
0
7
25
7
0
0
7
0
% D
% Glu:
38
13
0
7
0
7
13
0
7
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
0
0
25
0
7
0
13
0
7
% G
% His:
0
0
0
7
7
0
0
0
7
0
25
0
0
0
0
% H
% Ile:
7
0
0
7
0
7
0
0
0
0
0
19
0
19
0
% I
% Lys:
13
7
7
13
13
0
0
7
7
0
7
7
7
7
0
% K
% Leu:
7
13
7
19
13
0
0
32
0
0
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
32
0
0
7
% M
% Asn:
13
19
19
0
0
7
7
0
0
38
0
0
44
7
7
% N
% Pro:
7
0
7
38
0
38
0
7
0
0
13
19
0
7
7
% P
% Gln:
0
7
0
0
0
0
32
0
0
7
0
7
7
0
25
% Q
% Arg:
19
7
7
7
25
0
25
0
7
7
7
0
7
13
7
% R
% Ser:
0
0
7
0
0
7
7
32
0
19
0
0
25
32
32
% S
% Thr:
0
0
0
0
0
0
7
7
7
0
7
0
0
0
0
% T
% Val:
0
0
13
7
7
19
7
13
7
0
25
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
38
0
0
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _