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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3D
All Species:
36.36
Human Site:
Y455
Identified Species:
61.54
UniProt:
O15371
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15371
NP_003744.1
548
63973
Y455
K
L
G
Y
V
S
R
Y
H
V
K
D
S
S
R
Chimpanzee
Pan troglodytes
XP_001158987
547
63723
Y455
K
L
G
Y
V
S
R
Y
H
V
K
D
S
S
R
Rhesus Macaque
Macaca mulatta
XP_001083790
547
63709
Y455
K
L
G
Y
V
S
R
Y
H
V
K
D
S
S
R
Dog
Lupus familis
XP_850595
548
63914
Y455
K
L
G
Y
V
S
R
Y
H
V
K
D
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYK8
548
63970
Y455
K
L
G
Y
V
S
R
Y
H
V
K
D
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506069
668
76273
Y454
K
M
G
Y
V
S
R
Y
H
V
K
D
S
A
R
Chicken
Gallus gallus
XP_001234643
699
80199
Y609
K
L
G
Y
V
S
R
Y
H
V
K
D
S
A
R
Frog
Xenopus laevis
Q7ZTM9
550
63926
Y458
K
L
G
Y
V
S
R
Y
N
V
K
D
S
T
R
Zebra Danio
Brachydanio rerio
Q6TH15
552
64071
Y458
K
L
G
Y
V
S
R
Y
H
V
K
D
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCK0
560
63779
I462
K
L
G
Y
V
S
R
I
N
P
R
D
H
S
R
Honey Bee
Apis mellifera
XP_393057
562
64634
A470
K
F
G
Y
V
S
R
A
M
V
R
D
S
S
K
Nematode Worm
Caenorhab. elegans
P30642
570
64271
N482
K
L
G
Y
V
S
R
N
N
A
R
S
T
Q
N
Sea Urchin
Strong. purpuratus
XP_796913
549
63524
I454
K
F
G
Y
V
S
R
I
N
P
R
D
S
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P56820
591
66706
V474
K
I
G
F
V
S
R
V
H
P
R
D
H
F
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.2
99
N.A.
N.A.
98.9
N.A.
73.8
72.5
89.4
90.4
N.A.
56.7
60.5
45.7
63.2
Protein Similarity:
100
99.4
99.4
99.8
N.A.
N.A.
99.8
N.A.
77.4
76.3
96.7
96.7
N.A.
73.3
77
63.5
82.3
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
86.6
93.3
86.6
100
N.A.
66.6
66.6
46.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
100
100
N.A.
80
80
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
8
0
0
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
15
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
65
0
0
0
15
0
0
% H
% Ile:
0
8
0
0
0
0
0
15
0
0
0
0
0
0
0
% I
% Lys:
100
0
0
0
0
0
0
0
0
0
65
0
0
0
15
% K
% Leu:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
29
0
0
0
0
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
100
0
0
0
36
0
0
0
72
% R
% Ser:
0
0
0
0
0
100
0
0
0
0
0
8
79
58
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% T
% Val:
0
0
0
0
100
0
0
8
0
72
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
93
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _