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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3D
All Species:
45.76
Human Site:
T85
Identified Species:
77.44
UniProt:
O15371
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15371
NP_003744.1
548
63973
T85
S
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Chimpanzee
Pan troglodytes
XP_001158987
547
63723
T85
S
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Rhesus Macaque
Macaca mulatta
XP_001083790
547
63709
T85
S
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Dog
Lupus familis
XP_850595
548
63914
T85
T
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYK8
548
63970
T85
T
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506069
668
76273
T85
T
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Chicken
Gallus gallus
XP_001234643
699
80199
T238
T
S
F
Q
L
V
D
T
A
R
T
Q
K
T
A
Frog
Xenopus laevis
Q7ZTM9
550
63926
T85
T
S
F
Q
L
V
D
T
T
K
M
Q
K
T
A
Zebra Danio
Brachydanio rerio
Q6TH15
552
64071
T85
A
S
F
Q
L
V
D
T
A
K
T
Q
K
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCK0
560
63779
T95
T
T
F
H
L
V
D
T
A
R
V
Q
K
P
P
Honey Bee
Apis mellifera
XP_393057
562
64634
T102
T
T
F
H
L
V
D
T
T
R
V
Q
K
P
P
Nematode Worm
Caenorhab. elegans
P30642
570
64271
F88
H
G
M
D
E
H
N
F
Q
L
V
D
T
S
K
Sea Urchin
Strong. purpuratus
XP_796913
549
63524
T86
S
S
F
Q
L
V
D
T
S
K
V
Q
K
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P56820
591
66706
G115
A
A
F
R
L
V
D
G
K
P
P
P
R
P
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.2
99
N.A.
N.A.
98.9
N.A.
73.8
72.5
89.4
90.4
N.A.
56.7
60.5
45.7
63.2
Protein Similarity:
100
99.4
99.4
99.8
N.A.
N.A.
99.8
N.A.
77.4
76.3
96.7
96.7
N.A.
73.3
77
63.5
82.3
P-Site Identity:
100
100
100
93.3
N.A.
N.A.
93.3
N.A.
93.3
93.3
73.3
86.6
N.A.
60
53.3
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
86.6
100
N.A.
73.3
66.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
0
0
0
65
0
0
0
0
0
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
93
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
93
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
8
0
0
15
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
22
0
0
86
0
15
% K
% Leu:
0
0
0
0
93
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
8
0
29
15
% P
% Gln:
0
0
0
72
0
0
0
0
8
0
0
86
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
65
0
0
8
0
0
% R
% Ser:
29
72
0
0
0
0
0
0
8
0
0
0
0
8
0
% S
% Thr:
50
15
0
0
0
0
0
86
15
0
58
0
8
65
0
% T
% Val:
0
0
0
0
0
93
0
0
0
0
29
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _