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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3D
All Species:
13.07
Human Site:
T548
Identified Species:
22.12
UniProt:
O15371
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15371
NP_003744.1
548
63973
T548
E
E
E
E
E
E
E
T
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001158987
547
63723
A545
E
E
E
E
E
E
E
A
G
E
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001083790
547
63709
A545
E
E
E
E
E
E
E
A
G
D
_
_
_
_
_
Dog
Lupus familis
XP_850595
548
63914
T548
E
E
E
E
E
E
E
T
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYK8
548
63970
T548
E
E
E
E
E
E
E
T
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506069
668
76273
G543
D
E
E
E
E
E
E
G
E
R
P
P
A
E
E
Chicken
Gallus gallus
XP_001234643
699
80199
G698
E
E
E
E
E
E
E
G
L
_
_
_
_
_
_
Frog
Xenopus laevis
Q7ZTM9
550
63926
S550
E
E
V
E
E
E
E
S
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Q6TH15
552
64071
N552
D
E
E
E
D
E
D
N
_
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCK0
560
63779
V552
D
D
E
G
F
Q
Q
V
Y
N
Y
A
H
N
K
Honey Bee
Apis mellifera
XP_393057
562
64634
A559
D
D
E
P
V
N
D
A
F
Q
S
_
_
_
_
Nematode Worm
Caenorhab. elegans
P30642
570
64271
Sea Urchin
Strong. purpuratus
XP_796913
549
63524
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P56820
591
66706
A589
E
E
K
K
A
D
D
A
Q
A
_
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.2
99
N.A.
N.A.
98.9
N.A.
73.8
72.5
89.4
90.4
N.A.
56.7
60.5
45.7
63.2
Protein Similarity:
100
99.4
99.4
99.8
N.A.
N.A.
99.8
N.A.
77.4
76.3
96.7
96.7
N.A.
73.3
77
63.5
82.3
P-Site Identity:
100
70
70
100
N.A.
N.A.
100
N.A.
40
77.7
75
50
N.A.
6.6
9
0
0
P-Site Similarity:
100
80
80
100
N.A.
N.A.
100
N.A.
46.6
77.7
87.5
87.5
N.A.
46.6
36.3
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
29
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
15
0
0
8
8
22
0
0
8
0
0
0
0
0
% D
% Glu:
58
72
72
65
58
65
58
0
8
8
0
0
0
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
15
15
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
36
43
65
72
72
72
72
% _