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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3D
All Species:
49.39
Human Site:
S308
Identified Species:
83.59
UniProt:
O15371
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15371
NP_003744.1
548
63973
S308
D
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Chimpanzee
Pan troglodytes
XP_001158987
547
63723
S308
D
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Rhesus Macaque
Macaca mulatta
XP_001083790
547
63709
S308
D
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Dog
Lupus familis
XP_850595
548
63914
S308
D
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYK8
548
63970
S308
D
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506069
668
76273
S308
D
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Chicken
Gallus gallus
XP_001234643
699
80199
S462
E
E
G
N
S
F
N
S
P
R
N
L
A
M
E
Frog
Xenopus laevis
Q7ZTM9
550
63926
S311
D
E
V
N
S
L
N
S
P
R
N
L
A
M
E
Zebra Danio
Brachydanio rerio
Q6TH15
552
64071
S311
D
E
G
S
S
L
N
S
P
R
N
L
A
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCK0
560
63779
S314
D
D
D
S
S
C
N
S
P
R
N
L
A
I
E
Honey Bee
Apis mellifera
XP_393057
562
64634
S324
D
D
G
N
S
L
N
S
P
R
N
L
A
L
E
Nematode Worm
Caenorhab. elegans
P30642
570
64271
N328
E
P
P
S
F
D
G
N
G
I
N
N
A
K
D
Sea Urchin
Strong. purpuratus
XP_796913
549
63524
S308
D
E
G
T
H
M
N
S
P
R
N
L
G
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P56820
591
66706
S332
E
S
K
D
D
I
N
S
A
H
S
L
G
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.2
99
N.A.
N.A.
98.9
N.A.
73.8
72.5
89.4
90.4
N.A.
56.7
60.5
45.7
63.2
Protein Similarity:
100
99.4
99.4
99.8
N.A.
N.A.
99.8
N.A.
77.4
76.3
96.7
96.7
N.A.
73.3
77
63.5
82.3
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
93.3
86.6
86.6
N.A.
66.6
80
13.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
86.6
93.3
N.A.
86.6
93.3
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
86
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
79
15
8
8
8
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
22
72
0
0
0
0
0
0
0
0
0
0
0
0
93
% E
% Phe:
0
0
0
0
8
50
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
72
0
0
0
8
0
8
0
0
0
15
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
22
0
0
0
0
0
93
0
15
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
65
0
% M
% Asn:
0
0
0
65
0
0
93
8
0
0
93
8
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
86
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% R
% Ser:
0
8
0
22
79
0
0
93
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _