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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1G
All Species:
27.88
Human Site:
Y405
Identified Species:
47.18
UniProt:
O15355
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15355
NP_002698.1
546
59272
Y405
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Chimpanzee
Pan troglodytes
XP_525722
519
56359
Y378
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Rhesus Macaque
Macaca mulatta
XP_001095543
547
59396
Y406
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Dog
Lupus familis
XP_532910
544
58915
Y403
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61074
542
58710
Y402
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Rat
Rattus norvegicus
P20650
382
42398
G246
D
G
I
W
D
V
M
G
N
E
E
L
C
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508523
760
82402
T616
N
E
E
D
E
D
D
T
E
E
A
E
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080301
544
59025
Y408
R
A
I
G
D
H
F
Y
K
R
N
K
N
L
P
Zebra Danio
Brachydanio rerio
NP_958896
495
53309
L359
V
S
E
K
G
K
A
L
D
M
S
Y
D
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4Q5
662
72351
Y470
R
A
L
G
D
H
A
Y
K
T
N
V
T
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49595
491
53123
K355
V
D
L
S
V
D
H
K
P
E
D
E
V
E
T
Sea Urchin
Strong. purpuratus
XP_001175751
308
33905
H172
L
S
R
A
F
G
D
H
C
Y
K
M
T
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
G219
A
G
G
F
I
H
A
G
R
I
N
G
S
L
N
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
S332
I
F
D
F
H
D
F
S
D
D
D
N
E
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.6
96.6
N.A.
93.9
22.1
N.A.
26.9
N.A.
71.9
64.6
N.A.
34.2
N.A.
37.3
34.9
Protein Similarity:
100
94.6
99.6
97.6
N.A.
96.5
36.6
N.A.
38
N.A.
80.9
72.5
N.A.
52.5
N.A.
53.6
43.5
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
0
N.A.
100
0
N.A.
66.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
N.A.
100
20
N.A.
73.3
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
8
0
0
22
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
8
8
8
8
58
22
15
0
15
8
15
0
8
8
0
% D
% Glu:
0
8
15
0
8
0
0
0
8
22
8
15
15
15
8
% E
% Phe:
0
8
0
15
8
0
50
0
0
0
0
0
0
0
15
% F
% Gly:
0
15
8
50
8
8
0
15
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
8
58
8
8
0
0
0
0
0
8
0
% H
% Ile:
8
0
50
0
8
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
8
50
0
8
43
0
0
8
% K
% Leu:
8
0
15
0
0
0
0
8
0
0
0
8
0
58
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
58
8
43
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
8
0
0
0
0
0
8
43
0
0
0
0
0
% R
% Ser:
0
15
0
8
0
0
0
8
0
0
8
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
15
8
8
% T
% Val:
15
0
0
0
8
8
0
0
0
0
0
8
8
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _