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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1G
All Species:
23.64
Human Site:
S537
Identified Species:
40
UniProt:
O15355
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15355
NP_002698.1
546
59272
S537
G
A
E
E
N
G
N
S
D
K
K
K
K
A
K
Chimpanzee
Pan troglodytes
XP_525722
519
56359
S510
G
A
E
E
N
G
N
S
D
K
K
K
K
A
K
Rhesus Macaque
Macaca mulatta
XP_001095543
547
59396
S538
G
A
E
E
N
G
N
S
D
K
K
K
K
A
K
Dog
Lupus familis
XP_532910
544
58915
S535
G
A
E
E
N
G
N
S
D
I
K
K
K
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61074
542
58710
S534
G
A
E
D
T
G
N
S
D
K
K
K
A
K
R
Rat
Rattus norvegicus
P20650
382
42398
S375
Y
K
N
D
D
T
D
S
A
S
T
D
D
M
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508523
760
82402
H749
V
L
T
L
N
E
D
H
D
F
M
V
I
A
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080301
544
59025
S537
S
A
E
T
C
S
N
S
S
K
K
P
K
R
D
Zebra Danio
Brachydanio rerio
NP_958896
495
53309
D488
L
A
P
D
T
S
G
D
S
K
K
P
K
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4Q5
662
72351
K602
L
N
D
Q
S
A
S
K
R
C
A
S
Q
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49595
491
53123
T484
D
N
M
T
V
I
C
T
T
F
D
R
K
S
K
Sea Urchin
Strong. purpuratus
XP_001175751
308
33905
T301
A
E
D
K
P
E
E
T
D
S
K
K
P
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
E348
D
S
K
P
E
P
S
E
D
E
P
S
S
S
S
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
G461
K
N
E
N
A
K
K
G
S
K
I
E
E
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.6
96.6
N.A.
93.9
22.1
N.A.
26.9
N.A.
71.9
64.6
N.A.
34.2
N.A.
37.3
34.9
Protein Similarity:
100
94.6
99.6
97.6
N.A.
96.5
36.6
N.A.
38
N.A.
80.9
72.5
N.A.
52.5
N.A.
53.6
43.5
P-Site Identity:
100
100
100
93.3
N.A.
66.6
6.6
N.A.
20
N.A.
46.6
26.6
N.A.
0
N.A.
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
26.6
N.A.
26.6
N.A.
46.6
40
N.A.
33.3
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
0
8
8
0
0
8
0
8
0
8
36
8
% A
% Cys:
0
0
0
0
8
0
8
0
0
8
0
0
0
0
8
% C
% Asp:
15
0
15
22
8
0
15
8
58
0
8
8
8
0
8
% D
% Glu:
0
8
50
29
8
15
8
8
0
8
0
8
8
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
36
0
0
0
0
36
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
8
0
8
8
0
% I
% Lys:
8
8
8
8
0
8
8
8
0
50
58
43
50
8
36
% K
% Leu:
15
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
22
8
8
36
0
43
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
8
8
8
0
0
0
0
8
15
8
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
8
0
15
8
% R
% Ser:
8
8
0
0
8
15
15
50
22
15
0
15
8
15
8
% S
% Thr:
0
0
8
15
15
8
0
15
8
0
8
0
0
8
0
% T
% Val:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _