KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1G
All Species:
14.55
Human Site:
S218
Identified Species:
24.62
UniProt:
O15355
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15355
NP_002698.1
546
59272
S218
Y
T
G
F
S
S
N
S
E
R
G
T
E
A
G
Chimpanzee
Pan troglodytes
XP_525722
519
56359
Q199
E
R
G
T
E
A
G
Q
V
G
E
P
G
I
P
Rhesus Macaque
Macaca mulatta
XP_001095543
547
59396
S218
Y
T
G
F
S
S
N
S
E
R
G
T
E
A
G
Dog
Lupus familis
XP_532910
544
58915
S218
H
A
G
L
S
S
N
S
E
R
G
T
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61074
542
58710
S218
H
T
G
F
S
S
N
S
E
H
G
T
E
A
G
Rat
Rattus norvegicus
P20650
382
42398
N81
H
L
L
D
H
I
T
N
N
Q
D
F
K
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508523
760
82402
P424
D
A
G
I
S
S
G
P
R
R
G
A
R
A
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080301
544
59025
S228
G
S
S
P
K
A
G
S
L
R
P
K
A
V
P
Zebra Danio
Brachydanio rerio
NP_958896
495
53309
S194
G
E
T
E
C
G
P
S
V
A
D
S
I
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4Q5
662
72351
K282
T
L
V
S
S
S
N
K
K
L
F
A
T
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49595
491
53123
D190
E
E
E
A
E
E
Q
D
D
T
E
E
K
K
E
Sea Urchin
Strong. purpuratus
XP_001175751
308
33905
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
G54
D
D
K
T
S
F
F
G
V
Y
D
G
H
G
G
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
K167
K
P
T
L
L
S
E
K
S
R
I
V
A
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
99.6
96.6
N.A.
93.9
22.1
N.A.
26.9
N.A.
71.9
64.6
N.A.
34.2
N.A.
37.3
34.9
Protein Similarity:
100
94.6
99.6
97.6
N.A.
96.5
36.6
N.A.
38
N.A.
80.9
72.5
N.A.
52.5
N.A.
53.6
43.5
P-Site Identity:
100
6.6
100
80
N.A.
86.6
0
N.A.
40
N.A.
13.3
6.6
N.A.
20
N.A.
0
0
P-Site Similarity:
100
13.3
100
86.6
N.A.
93.3
26.6
N.A.
40
N.A.
26.6
13.3
N.A.
26.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
15
0
0
0
8
0
15
15
43
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
0
8
0
0
0
8
8
0
22
0
0
0
8
% D
% Glu:
15
15
8
8
15
8
8
0
29
0
15
8
29
0
15
% E
% Phe:
0
0
0
22
0
8
8
0
0
0
8
8
0
0
0
% F
% Gly:
15
0
43
0
0
8
22
8
0
8
36
8
8
29
36
% G
% His:
22
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
8
0
8
8
0
% I
% Lys:
8
0
8
0
8
0
0
15
8
0
0
8
15
8
8
% K
% Leu:
0
15
8
15
8
0
0
0
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
36
8
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
8
8
0
0
8
8
0
0
15
% P
% Gln:
0
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
43
0
0
8
0
0
% R
% Ser:
0
8
8
8
50
50
0
43
8
0
0
8
0
0
15
% S
% Thr:
8
22
15
15
0
0
8
0
0
8
0
29
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
22
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _