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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP4B
All Species:
22.12
Human Site:
S258
Identified Species:
54.07
UniProt:
O15327
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15327
NP_001095139.1
924
104738
S258
I
R
E
Q
M
S
E
S
I
L
S
F
H
I
P
Chimpanzee
Pan troglodytes
XP_001141569
924
104637
S258
I
R
E
Q
M
S
E
S
I
L
S
F
H
I
P
Rhesus Macaque
Macaca mulatta
XP_001091997
924
104759
S258
I
R
E
Q
M
S
E
S
I
L
S
F
H
I
P
Dog
Lupus familis
XP_533280
930
104345
S263
I
R
E
Q
M
S
E
S
I
L
S
F
H
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1Y8
924
104513
H246
S
E
S
I
L
S
F
H
I
P
K
E
L
I
S
Rat
Rattus norvegicus
Q9QWG5
928
105227
S258
I
R
E
Q
M
S
E
S
I
L
S
F
H
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513091
890
100607
D245
R
R
N
Q
E
L
K
D
L
G
E
L
S
P
H
Chicken
Gallus gallus
XP_420420
904
102330
H246
A
E
T
I
L
S
F
H
V
P
K
E
L
I
N
Frog
Xenopus laevis
NP_001089588
929
105035
S248
I
L
E
Q
M
A
E
S
V
L
S
L
H
I
P
Zebra Danio
Brachydanio rerio
NP_001139046
827
93487
K213
K
L
T
G
P
S
F
K
P
S
C
S
K
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
89.5
N.A.
85.8
90.4
N.A.
81.2
78.1
43.1
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.3
93.3
N.A.
90.5
95.2
N.A.
88.3
86.6
62.4
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
20
100
N.A.
13.3
13.3
73.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
26.6
26.6
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
20
60
0
10
0
60
0
0
0
10
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
30
0
0
0
0
50
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
0
60
0
10
% H
% Ile:
60
0
0
20
0
0
0
0
60
0
0
0
0
80
0
% I
% Lys:
10
0
0
0
0
0
10
10
0
0
20
0
10
0
0
% K
% Leu:
0
20
0
0
20
10
0
0
10
60
0
20
20
0
0
% L
% Met:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
10
20
0
0
0
10
60
% P
% Gln:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
0
80
0
60
0
10
60
10
10
0
10
% S
% Thr:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _