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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1D
All Species:
21.82
Human Site:
S327
Identified Species:
40
UniProt:
O15297
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15297
NP_003611.1
605
66675
S327
I
P
P
Q
D
A
I
S
M
C
Q
D
Q
E
E
Chimpanzee
Pan troglodytes
XP_511612
605
66629
S327
I
P
P
Q
D
A
I
S
M
C
Q
D
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001110891
605
66558
S327
I
P
P
Q
D
A
I
S
M
C
Q
D
Q
E
E
Dog
Lupus familis
XP_852759
729
79555
S451
I
P
P
Q
D
A
I
S
M
C
Q
D
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ67
598
65704
S320
V
P
P
Q
D
A
I
S
M
C
Q
D
Q
E
E
Rat
Rattus norvegicus
P20650
382
42398
H120
R
V
M
S
E
K
K
H
G
A
D
R
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510733
468
51371
L206
G
Q
S
C
A
K
M
L
V
N
R
A
L
G
R
Chicken
Gallus gallus
XP_415890
478
52722
H216
K
K
Y
F
M
G
E
H
R
Q
S
C
A
K
M
Frog
Xenopus laevis
NP_001085562
554
61512
S290
V
S
A
Q
D
A
I
S
M
C
Q
E
Q
E
R
Zebra Danio
Brachydanio rerio
NP_001007341
534
58704
F272
T
P
I
D
Q
I
P
F
L
A
V
A
R
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525074
1427
153887
D518
V
T
A
Q
E
A
V
D
S
V
R
K
E
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
E94
G
N
M
K
E
A
I
E
K
G
F
L
E
L
D
Sea Urchin
Strong. purpuratus
XP_787213
568
64302
L287
L
V
K
R
G
M
D
L
W
N
Y
H
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.5
78.3
N.A.
88.2
21.4
N.A.
59.6
60.9
59.1
49.4
N.A.
20.7
N.A.
20.6
31.5
Protein Similarity:
100
99.6
98.8
79.9
N.A.
92.7
33.5
N.A.
65.4
66.7
72.5
62.4
N.A.
29.5
N.A.
33.2
49.5
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
0
0
66.6
6.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
20
6.6
80
20
N.A.
46.6
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
62
0
0
0
16
0
16
8
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
47
0
8
0
0
0
% C
% Asp:
0
0
0
8
47
0
8
8
0
0
8
39
0
0
8
% D
% Glu:
0
0
0
0
24
0
8
8
0
0
0
8
16
47
39
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
16
0
0
0
8
8
0
0
8
8
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
8
0
8
0
% H
% Ile:
31
0
8
0
0
8
54
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
8
0
16
8
0
8
0
0
8
0
8
0
% K
% Leu:
8
0
0
0
0
0
0
16
8
0
0
8
16
16
16
% L
% Met:
0
0
16
0
8
8
8
0
47
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
0
47
39
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
54
8
0
0
0
0
8
47
0
47
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
8
0
16
8
8
0
24
% R
% Ser:
0
8
8
8
0
0
0
47
8
0
8
0
8
0
8
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
24
16
0
0
0
0
8
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _