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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASC3
All Species:
30.91
Human Site:
Y547
Identified Species:
85
UniProt:
O15234
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15234
NP_031385.2
703
76278
Y547
I
S
I
M
E
G
H
Y
Y
D
P
L
Q
F
Q
Chimpanzee
Pan troglodytes
XP_511470
633
69498
Y477
I
S
I
M
E
G
H
Y
Y
D
P
L
Q
F
Q
Rhesus Macaque
Macaca mulatta
XP_001096548
704
76487
Y548
I
S
I
M
E
G
H
Y
Y
D
P
L
Q
F
Q
Dog
Lupus familis
XP_537649
703
76251
Y547
I
S
I
M
E
G
H
Y
Y
D
P
L
Q
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3W3
698
75752
Y542
I
S
I
M
E
G
H
Y
Y
D
P
L
Q
F
Q
Rat
Rattus norvegicus
Q8K3X0
699
75886
Y543
I
S
I
M
E
G
H
Y
Y
D
P
L
Q
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423806
573
63459
E430
T
P
K
P
I
Q
A
E
T
S
P
P
P
A
K
Frog
Xenopus laevis
A0JMU8
686
76943
Y524
I
S
L
M
E
S
H
Y
Y
D
P
L
Q
F
Q
Zebra Danio
Brachydanio rerio
Q1ECZ4
754
82725
Y593
I
G
V
M
E
G
H
Y
Y
E
P
M
T
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
97.5
95.4
N.A.
90.3
91.6
N.A.
N.A.
55.3
56.6
45.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.7
98.1
96.3
N.A.
93
94
N.A.
N.A.
62.4
69.9
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
86.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% D
% Glu:
0
0
0
0
89
0
0
12
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
89
0
% F
% Gly:
0
12
0
0
0
78
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
89
0
0
0
0
0
0
0
0
% H
% Ile:
89
0
67
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
78
0
0
0
% L
% Met:
0
0
0
89
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
12
0
0
0
0
0
0
100
12
12
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
78
0
89
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
78
0
0
0
12
0
0
0
12
0
0
0
0
0
% S
% Thr:
12
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
89
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _