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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARPC1B All Species: 27.27
Human Site: T144 Identified Species: 54.55
UniProt: O15143 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15143 NP_005711.1 372 40950 T144 I K K P I R S T V L S L D W H
Chimpanzee Pan troglodytes XP_519230 562 60557 T334 I K K P I R S T V L S L D W H
Rhesus Macaque Macaca mulatta XP_001111652 364 39827 T136 I K K P I R S T V L S L D W H
Dog Lupus familis XP_536872 372 41045 T144 I K K P I R S T V L S L D W H
Cat Felis silvestris
Mouse Mus musculus Q9WV32 372 41130 T144 I K K P I R S T V L S L D W H
Rat Rattus norvegicus O88656 372 41038 T144 I K K P I R S T V L S L D W H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511730 368 41086 P140 V C K H I K K P I R S T V L S
Chicken Gallus gallus NP_001025803 369 41049 I141 C K H I K K P I R S T V L S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790807 367 40833 K140 W V S K H I K K P I R S T V T
Poplar Tree Populus trichocarpa
Maize Zea mays P49178 380 41696 V149 D R D G N M P V S R I L T G H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49177 377 40987 S149 K D G T V P V S R M L T G H R
Baker's Yeast Sacchar. cerevisiae P38328 384 42456 T155 I K K P I K S T I N C L S W H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66 94.6 96.2 N.A. 97 96.7 N.A. 89.5 88.1 N.A. N.A. N.A. N.A. N.A. N.A. 51.6
Protein Similarity: 100 66 95.4 98.1 N.A. 97.8 98.1 N.A. 95.1 95.1 N.A. N.A. N.A. N.A. N.A. N.A. 70.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 20 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 40 26.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. 23.1 N.A. 22.5 36.9 N.A.
Protein Similarity: N.A. 37.1 N.A. 34.7 53.1 N.A.
P-Site Identity: N.A. 13.3 N.A. 0 66.6 N.A.
P-Site Similarity: N.A. 20 N.A. 20 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 9 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 9 9 9 0 0 0 0 0 0 0 0 0 50 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 0 0 0 0 0 0 0 0 9 9 0 % G
% His: 0 0 9 9 9 0 0 0 0 0 0 0 0 9 67 % H
% Ile: 59 0 0 9 67 9 0 9 17 9 9 0 0 0 0 % I
% Lys: 9 67 67 9 9 25 17 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 50 9 67 9 9 9 % L
% Met: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 59 0 9 17 9 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 50 0 0 17 17 9 0 0 0 9 % R
% Ser: 0 0 9 0 0 0 59 9 9 9 59 9 9 9 9 % S
% Thr: 0 0 0 9 0 0 0 59 0 0 9 17 17 0 9 % T
% Val: 9 9 0 0 9 0 9 9 50 0 0 9 9 9 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 59 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _