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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARPC1B All Species: 32.42
Human Site: S343 Identified Species: 64.85
UniProt: O15143 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15143 NP_005711.1 372 40950 S343 S G G K A K C S Q F C T T G M
Chimpanzee Pan troglodytes XP_519230 562 60557 S533 S G G K A K C S Q F C T T G M
Rhesus Macaque Macaca mulatta XP_001111652 364 39827 S335 S G G K A K C S Q F C T T G M
Dog Lupus familis XP_536872 372 41045 S343 S G G K A E C S Q F C T T G M
Cat Felis silvestris
Mouse Mus musculus Q9WV32 372 41130 S343 S G G K A K C S Q F C T T G M
Rat Rattus norvegicus O88656 372 41038 S343 S G G K A K C S Q F C T T G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511730 368 41086 S339 A G G K A K C S Q F C T T G M
Chicken Gallus gallus NP_001025803 369 41049 S340 V G G K A N C S Q F C T T G M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790807 367 40833 A339 T G E K E A I A K L S S V G M
Poplar Tree Populus trichocarpa
Maize Zea mays P49178 380 41696 S348 N S H D G R I S C L G M S S D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49177 377 40987 G348 R N R I S C L G L S A D G S A
Baker's Yeast Sacchar. cerevisiae P38328 384 42456 I354 E S A H E N A I V E L R P F A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66 94.6 96.2 N.A. 97 96.7 N.A. 89.5 88.1 N.A. N.A. N.A. N.A. N.A. N.A. 51.6
Protein Similarity: 100 66 95.4 98.1 N.A. 97.8 98.1 N.A. 95.1 95.1 N.A. N.A. N.A. N.A. N.A. N.A. 70.1
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. 23.1 N.A. 22.5 36.9 N.A.
Protein Similarity: N.A. 37.1 N.A. 34.7 53.1 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 0 N.A.
P-Site Similarity: N.A. 26.6 N.A. 6.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 67 9 9 9 0 0 9 0 0 0 17 % A
% Cys: 0 0 0 0 0 9 67 0 9 0 67 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 9 % D
% Glu: 9 0 9 0 17 9 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 67 0 0 0 9 0 % F
% Gly: 0 75 67 0 9 0 0 9 0 0 9 0 9 75 0 % G
% His: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 17 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 75 0 50 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 9 17 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 75 % M
% Asn: 9 9 0 0 0 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % Q
% Arg: 9 0 9 0 0 9 0 0 0 0 0 9 0 0 0 % R
% Ser: 50 17 0 0 9 0 0 75 0 9 9 9 9 17 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 67 67 0 0 % T
% Val: 9 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _