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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARPC1B All Species: 23.94
Human Site: S292 Identified Species: 47.88
UniProt: O15143 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15143 NP_005711.1 372 40950 S292 L D V P K Q S S Q R G L T A R
Chimpanzee Pan troglodytes XP_519230 562 60557 S482 L D V P K Q S S Q R G L T A R
Rhesus Macaque Macaca mulatta XP_001111652 364 39827 S284 L D V P K Q S S Q R G L T A R
Dog Lupus familis XP_536872 372 41045 S292 L D V P K Q S S Q R G L T A R
Cat Felis silvestris
Mouse Mus musculus Q9WV32 372 41130 S292 L D V P K Q S S Q R G M T A R
Rat Rattus norvegicus O88656 372 41038 S292 L D V P K Q N S Q R G L T A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511730 368 41086 P288 F G G R M D V P K Q S S Q R G
Chicken Gallus gallus NP_001025803 369 41049 K289 G G K L D V P K Q S S Q R G L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790807 367 40833 A288 F E G K V S V A Q K K S A G T
Poplar Tree Populus trichocarpa
Maize Zea mays P49178 380 41696 E297 E P D R N S N E L P T V T S I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49177 377 40987 V297 G D G E N G P V T S I A F S V
Baker's Yeast Sacchar. cerevisiae P38328 384 42456 S303 K S D N N K S S A L T A S G N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66 94.6 96.2 N.A. 97 96.7 N.A. 89.5 88.1 N.A. N.A. N.A. N.A. N.A. N.A. 51.6
Protein Similarity: 100 66 95.4 98.1 N.A. 97.8 98.1 N.A. 95.1 95.1 N.A. N.A. N.A. N.A. N.A. N.A. 70.1
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 23.1 N.A. 22.5 36.9 N.A.
Protein Similarity: N.A. 37.1 N.A. 34.7 53.1 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 9 0 0 17 9 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 59 17 0 9 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 9 0 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 17 17 25 0 0 9 0 0 0 0 50 0 0 25 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % I
% Lys: 9 0 9 9 50 9 0 9 9 9 9 0 0 0 0 % K
% Leu: 50 0 0 9 0 0 0 0 9 9 0 42 0 0 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 9 25 0 17 0 0 0 0 0 0 0 9 % N
% Pro: 0 9 0 50 0 0 17 9 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 50 0 0 67 9 0 9 9 0 0 % Q
% Arg: 0 0 0 17 0 0 0 0 0 50 0 0 9 9 50 % R
% Ser: 0 9 0 0 0 17 50 59 0 17 17 17 9 17 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 17 0 59 0 9 % T
% Val: 0 0 50 0 9 9 17 9 0 0 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _