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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS3
All Species:
10.91
Human Site:
S1150
Identified Species:
30
UniProt:
O15072
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15072
NP_055058.1
1205
135575
S1150
R
L
V
T
V
P
S
S
P
P
T
K
R
V
H
Chimpanzee
Pan troglodytes
XP_517240
1205
135560
S1150
R
L
V
T
V
P
S
S
P
P
T
K
R
V
H
Rhesus Macaque
Macaca mulatta
XP_001104686
1205
135599
S1150
R
L
V
A
T
P
S
S
P
P
T
K
R
G
H
Dog
Lupus familis
XP_539311
1314
147280
T1195
L
R
L
V
S
P
A
T
K
S
G
P
L
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9W3
1213
135281
T1154
N
V
S
S
T
N
A
T
E
D
H
P
E
T
N
Rat
Rattus norvegicus
Q1EHB3
1595
175796
N1243
V
E
V
S
T
G
W
N
V
A
L
D
P
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505715
1189
133383
P1132
L
N
A
T
D
D
R
P
E
T
N
A
L
D
D
Chicken
Gallus gallus
XP_426316
1212
136699
P1154
L
F
A
L
L
H
Q
P
P
G
N
S
S
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697234
1164
131811
N1109
T
P
P
P
R
K
H
N
T
E
N
S
K
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.4
77.4
N.A.
52.9
25.2
N.A.
55.9
79.6
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.2
81.2
N.A.
67.2
38.4
N.A.
69.7
87.1
N.A.
81.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
0
13.3
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
26.6
N.A.
33.3
26.6
N.A.
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
12
0
0
23
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
12
0
0
0
12
0
12
0
12
12
% D
% Glu:
0
12
0
0
0
0
0
0
23
12
0
0
12
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
12
12
0
0
12
0
% G
% His:
0
0
0
0
0
12
12
0
0
0
12
0
0
0
34
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
12
0
0
34
12
0
0
% K
% Leu:
34
34
12
12
12
0
0
0
0
0
12
0
23
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
12
0
0
0
12
0
23
0
0
34
0
0
12
12
% N
% Pro:
0
12
12
12
0
45
0
23
45
34
0
23
12
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% Q
% Arg:
34
12
0
0
12
0
12
0
0
0
0
0
34
0
0
% R
% Ser:
0
0
12
23
12
0
34
34
0
12
0
23
12
12
12
% S
% Thr:
12
0
0
34
34
0
0
23
12
12
34
0
0
23
0
% T
% Val:
12
12
45
12
23
0
0
0
12
0
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _