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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AZIN1 All Species: 18.79
Human Site: Y342 Identified Species: 34.44
UniProt: O14977 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14977 NP_056962.2 448 49535 Y342 I P E V H K K Y K E D E P L F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082539 448 49497 Y342 I P E V H K K Y K E D E P L F
Dog Lupus familis XP_532293 447 49500 Y342 I P E V H K K Y K K D E P L F
Cat Felis silvestris
Mouse Mus musculus O35484 448 49531 Y342 I P E V H K K Y K E D E P L F
Rat Rattus norvegicus Q63764 448 49314 Y342 V P E V H K K Y K E D E P L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506230 301 32893 C202 K F H V S S S C K E P Q V Y I
Chicken Gallus gallus P27118 450 49716 P334 K P V L Q K R P K P D D G C Y
Frog Xenopus laevis P27120 460 50811 P345 K P V L T K K P K P D E K F Y
Zebra Danio Brachydanio rerio NP_001007160 436 47675 V337 N I I S T P S V H K M S L T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40807 394 44176 D295 R N E A G K L D T V M Y Y L N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41931 422 46901 Y323 Y Y I N D G V Y G S F N C I L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P08432 466 52267 E366 C I L F D H Q E P H P R T L Y
Red Bread Mold Neurospora crassa P27121 484 53282 H383 F S S I M F D H Q H P V A K I
Conservation
Percent
Protein Identity: 100 N.A. 99.3 95.7 N.A. 95.7 93 N.A. 58.7 48 49.5 55.1 N.A. 33.2 N.A. 33.7 N.A.
Protein Similarity: 100 N.A. 99.7 98.4 N.A. 97.5 96.2 N.A. 63.8 65.7 67.3 70.5 N.A. 50 N.A. 53.5 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 93.3 N.A. 20 26.6 40 0 N.A. 20 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 26.6 53.3 53.3 6.6 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.6 30.3
Protein Similarity: N.A. N.A. N.A. N.A. 50.2 48.3
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % C
% Asp: 0 0 0 0 16 0 8 8 0 0 54 8 0 0 0 % D
% Glu: 0 0 47 0 0 0 0 8 0 39 0 47 0 0 0 % E
% Phe: 8 8 0 8 0 8 0 0 0 0 8 0 0 8 39 % F
% Gly: 0 0 0 0 8 8 0 0 8 0 0 0 8 0 0 % G
% His: 0 0 8 0 39 8 0 8 8 16 0 0 0 0 0 % H
% Ile: 31 16 16 8 0 0 0 0 0 0 0 0 0 8 16 % I
% Lys: 24 0 0 0 0 62 47 0 62 16 0 0 8 8 0 % K
% Leu: 0 0 8 16 0 0 8 0 0 0 0 0 8 54 16 % L
% Met: 0 0 0 0 8 0 0 0 0 0 16 0 0 0 0 % M
% Asn: 8 8 0 8 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 54 0 0 0 8 0 16 8 16 24 0 39 0 0 % P
% Gln: 0 0 0 0 8 0 8 0 8 0 0 8 0 0 0 % Q
% Arg: 8 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % R
% Ser: 0 8 8 8 8 8 16 0 0 8 0 8 0 0 0 % S
% Thr: 0 0 0 0 16 0 0 0 8 0 0 0 8 8 0 % T
% Val: 8 0 16 47 0 0 8 8 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 47 0 0 0 8 8 8 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _