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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AZIN1
All Species:
26.67
Human Site:
Y122
Identified Species:
48.89
UniProt:
O14977
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14977
NP_056962.2
448
49535
Y122
K
Q
V
S
Q
I
K
Y
A
A
K
V
G
V
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082539
448
49497
Y122
K
Q
V
S
Q
I
K
Y
A
A
K
V
G
V
N
Dog
Lupus familis
XP_532293
447
49500
Y122
K
Q
V
S
Q
I
K
Y
A
A
K
I
G
V
N
Cat
Felis silvestris
Mouse
Mus musculus
O35484
448
49531
Y122
K
Q
V
S
Q
I
K
Y
A
A
K
V
G
V
N
Rat
Rattus norvegicus
Q63764
448
49314
Y122
K
Q
A
S
Q
I
K
Y
A
A
K
V
G
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506230
301
32893
Chicken
Gallus gallus
P27118
450
49716
H112
K
Q
L
S
Q
I
K
H
A
A
N
S
G
V
R
Frog
Xenopus laevis
P27120
460
50811
Y122
K
Q
V
S
Q
I
K
Y
A
A
S
C
G
V
E
Zebra Danio
Brachydanio rerio
NP_001007160
436
47675
H122
K
Q
L
L
L
I
K
H
A
A
K
T
G
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40807
394
44176
E99
L
G
F
D
V
S
P
E
R
I
I
F
A
N
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41931
422
46901
H124
K
T
R
S
F
I
A
H
A
M
D
R
D
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08432
466
52267
Y169
K
V
A
S
F
I
R
Y
A
A
S
K
N
V
M
Red Bread Mold
Neurospora crassa
P27121
484
53282
Y167
K
T
N
S
Y
L
R
Y
V
A
Q
Q
G
V
R
Conservation
Percent
Protein Identity:
100
N.A.
99.3
95.7
N.A.
95.7
93
N.A.
58.7
48
49.5
55.1
N.A.
33.2
N.A.
33.7
N.A.
Protein Similarity:
100
N.A.
99.7
98.4
N.A.
97.5
96.2
N.A.
63.8
65.7
67.3
70.5
N.A.
50
N.A.
53.5
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
93.3
N.A.
0
66.6
80
60
N.A.
0
N.A.
33.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
0
80
80
80
N.A.
0
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.6
30.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
48.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
8
0
77
77
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
16
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
77
0
0
0
8
8
8
0
8
0
% I
% Lys:
85
0
0
0
0
0
62
0
0
0
47
8
0
0
8
% K
% Leu:
8
0
16
8
8
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
0
8
8
47
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
62
0
0
54
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
8
0
0
0
16
0
8
0
0
8
0
0
16
% R
% Ser:
0
0
0
77
0
8
0
0
0
0
16
8
0
0
0
% S
% Thr:
0
16
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
8
39
0
8
0
0
0
8
0
0
31
0
77
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _