KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AZIN1
All Species:
18.18
Human Site:
S274
Identified Species:
33.33
UniProt:
O14977
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14977
NP_056962.2
448
49535
S274
K
I
I
S
E
P
G
S
Y
Y
V
S
S
A
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082539
448
49497
S274
K
I
I
S
E
P
G
S
Y
Y
V
S
S
A
F
Dog
Lupus familis
XP_532293
447
49500
S274
K
I
I
S
E
P
G
S
Y
Y
V
S
S
A
F
Cat
Felis silvestris
Mouse
Mus musculus
O35484
448
49531
S274
Q
I
I
S
E
P
G
S
Y
Y
V
S
S
A
F
Rat
Rattus norvegicus
Q63764
448
49314
S274
Q
I
I
S
E
P
G
S
Y
Y
V
S
S
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506230
301
32893
M137
I
M
T
C
D
N
E
M
E
L
K
K
I
A
L
Chicken
Gallus gallus
P27118
450
49716
E264
S
E
V
T
I
I
A
E
P
G
R
Y
Y
V
A
Frog
Xenopus laevis
P27120
460
50811
R277
K
I
I
A
E
P
G
R
Y
Y
V
A
S
S
F
Zebra Danio
Brachydanio rerio
NP_001007160
436
47675
N272
S
I
I
A
E
P
G
N
F
F
V
F
S
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40807
394
44176
G230
M
D
F
L
D
I
G
G
G
F
P
G
S
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41931
422
46901
R258
E
K
I
A
E
T
I
R
D
A
L
D
E
F
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08432
466
52267
L301
E
S
T
A
V
L
R
L
A
L
E
E
F
F
P
Red Bread Mold
Neurospora crassa
P27121
484
53282
R318
N
L
I
A
E
P
G
R
Y
Y
A
S
S
A
F
Conservation
Percent
Protein Identity:
100
N.A.
99.3
95.7
N.A.
95.7
93
N.A.
58.7
48
49.5
55.1
N.A.
33.2
N.A.
33.7
N.A.
Protein Similarity:
100
N.A.
99.7
98.4
N.A.
97.5
96.2
N.A.
63.8
65.7
67.3
70.5
N.A.
50
N.A.
53.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
6.6
0
73.3
53.3
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
13.3
93.3
80
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.6
30.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.2
48.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
39
0
0
8
0
8
8
8
8
0
54
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
16
0
0
0
8
0
0
8
0
8
8
% D
% Glu:
16
8
0
0
70
0
8
8
8
0
8
8
8
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
16
0
8
8
16
70
% F
% Gly:
0
0
0
0
0
0
70
8
8
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
54
70
0
8
16
8
0
0
0
0
0
8
0
0
% I
% Lys:
31
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% K
% Leu:
0
8
0
8
0
8
0
8
0
16
8
0
0
0
8
% L
% Met:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
62
0
0
8
0
8
0
0
0
8
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
24
0
0
8
0
0
0
0
% R
% Ser:
16
8
0
39
0
0
0
39
0
0
0
47
70
8
0
% S
% Thr:
0
0
16
8
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
8
0
0
0
0
0
54
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
54
54
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _