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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAK All Species: 23.33
Human Site: T114 Identified Species: 64.17
UniProt: O14976 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14976 NP_005246.2 1311 143191 T114 I G K E E S D T G Q A E F L L
Chimpanzee Pan troglodytes XP_001140835 1311 143128 T114 I G K E E S D T G Q A E F L L
Rhesus Macaque Macaca mulatta XP_001094120 1194 129694 S88 I K L C D F G S A T T I S H Y
Dog Lupus familis XP_536279 800 86121
Cat Felis silvestris
Mouse Mus musculus Q99KY4 1305 143622 T114 I G K E E S D T G Q A E F L L
Rat Rattus norvegicus P97874 1305 143685 T114 I G K E E S D T G Q A E F L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512602 1331 147587 T114 I G K E E S D T G Q A E F L L
Chicken Gallus gallus XP_424873 1296 143627 K102 L L L T E L C K G Q L V E F L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919224 1278 141216 T114 I S K E E S D T G Q A E F L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 88.5 47.8 N.A. 82.6 82.3 N.A. 74.2 70.1 N.A. 66.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 89.2 52.1 N.A. 88.4 88.3 N.A. 83.3 80.3 N.A. 77.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 0 N.A. 100 100 N.A. 100 26.6 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 0 N.A. 100 100 N.A. 100 33.3 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 67 0 0 0 0 % A
% Cys: 0 0 0 12 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 67 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 67 78 0 0 0 0 0 0 67 12 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 67 12 0 % F
% Gly: 0 56 0 0 0 0 12 0 78 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 78 0 0 0 0 0 0 0 0 0 0 12 0 0 12 % I
% Lys: 0 12 67 0 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 12 12 23 0 0 12 0 0 0 0 12 0 0 67 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 0 0 0 67 0 12 0 0 0 0 12 0 0 % S
% Thr: 0 0 0 12 0 0 0 67 0 12 12 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _