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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASQ2
All Species:
32.42
Human Site:
Y217
Identified Species:
79.26
UniProt:
O14958
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14958
NP_001223.2
399
46436
Y217
K
M
N
E
V
D
F
Y
E
P
F
M
D
E
P
Chimpanzee
Pan troglodytes
XP_513677
429
49951
Y247
K
M
N
E
V
D
F
Y
E
P
F
M
D
E
P
Rhesus Macaque
Macaca mulatta
XP_001101353
394
45054
S205
T
F
D
K
G
R
V
S
S
P
F
L
G
L
H
Dog
Lupus familis
XP_540252
506
57591
Y313
K
M
N
E
V
D
F
Y
E
P
F
M
D
E
P
Cat
Felis silvestris
Mouse
Mus musculus
O09161
415
48179
Y217
K
M
N
E
V
G
F
Y
E
P
F
M
D
E
P
Rat
Rattus norvegicus
P51868
413
47820
Y217
K
M
N
E
V
G
F
Y
E
P
F
M
D
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19204
406
47133
Y217
K
M
N
E
V
D
F
Y
E
P
F
M
D
E
P
Frog
Xenopus laevis
NP_001080227
428
49301
Y220
K
I
N
E
I
D
Y
Y
E
P
F
H
D
E
P
Zebra Danio
Brachydanio rerio
NP_001002682
409
47312
Y218
K
M
N
E
V
D
F
Y
E
P
F
M
E
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510438
417
48308
R226
R
V
G
E
V
Q
M
R
R
P
F
E
E
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.8
84.4
73.7
N.A.
86.5
88.3
N.A.
N.A.
78.5
59.5
68.2
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
100
90.9
88.4
77.8
N.A.
92.2
92.7
N.A.
N.A.
89.4
77.5
84.3
N.A.
N.A.
N.A.
53.4
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
N.A.
100
73.3
93.3
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
93.3
93.3
N.A.
N.A.
100
93.3
100
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
60
0
0
0
0
0
0
70
10
0
% D
% Glu:
0
0
0
90
0
0
0
0
80
0
0
10
20
80
0
% E
% Phe:
0
10
0
0
0
0
70
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
10
0
10
20
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
80
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
70
0
0
0
0
10
0
0
0
0
70
0
0
0
% M
% Asn:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
90
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
80
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _