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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD2 All Species: 18.48
Human Site: T222 Identified Species: 40.67
UniProt: O14939 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14939 NP_002654.3 933 105987 T222 G H R V P G L T C C G R D Q V
Chimpanzee Pan troglodytes XP_511291 924 105027 T222 G H R V P G L T C C G R D Q V
Rhesus Macaque Macaca mulatta XP_001117754 892 101098 T221 G H R V P G L T C C G R D Q V
Dog Lupus familis XP_536610 854 96426 A212 P P A R E A A A D R E I P S L
Cat Felis silvestris
Mouse Mus musculus P97813 933 106150 T222 G H R V P G F T F C G R D Q V
Rat Rattus norvegicus P70498 933 106019 T222 G H R V P G F T C C G R D Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422793 1072 123414 N237 G H R I P G L N C C G Q G R M
Frog Xenopus laevis NP_001129642 1039 119219 N240 G H R I P G L N C C G Q G S V
Zebra Danio Brachydanio rerio XP_694649 927 106849 I214 R I Q G L N C I G H H Q F C F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194932 825 94056 V183 D Q D L K V A V G R E N T G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 T242 G V R C C L P T H C L G F F G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 92.1 77.2 N.A. 90 89.5 N.A. N.A. 48.8 50.9 59.2 N.A. N.A. N.A. N.A. 36.2
Protein Similarity: 100 97.2 93.7 80.7 N.A. 93.8 93.1 N.A. N.A. 63.3 66.2 73.5 N.A. N.A. N.A. N.A. 53.1
P-Site Identity: 100 100 100 0 N.A. 86.6 93.3 N.A. N.A. 60 66.6 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 6.6 N.A. 86.6 93.3 N.A. N.A. 86.6 80 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 31.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 19 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 10 0 10 0 55 73 0 0 0 10 0 % C
% Asp: 10 0 10 0 0 0 0 0 10 0 0 0 46 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 19 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 19 0 10 0 0 0 19 10 10 % F
% Gly: 73 0 0 10 0 64 0 0 19 0 64 10 19 10 10 % G
% His: 0 64 0 0 0 0 0 0 10 10 10 0 0 0 0 % H
% Ile: 0 10 0 19 0 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 10 10 46 0 0 0 10 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 10 0 19 0 0 0 10 0 0 0 % N
% Pro: 10 10 0 0 64 0 10 0 0 0 0 0 10 0 0 % P
% Gln: 0 10 10 0 0 0 0 0 0 0 0 28 0 46 0 % Q
% Arg: 10 0 73 10 0 0 0 0 0 19 0 46 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % S
% Thr: 0 0 0 0 0 0 0 55 0 0 0 0 10 0 0 % T
% Val: 0 10 0 46 0 10 0 10 0 0 0 0 0 0 55 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _