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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF1
All Species:
6.36
Human Site:
Y540
Identified Species:
15.56
UniProt:
O14829
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14829
NP_006231.2
653
75792
Y540
D
Q
N
G
N
V
E
Y
M
S
S
F
Q
N
I
Chimpanzee
Pan troglodytes
XP_526584
753
86517
K626
A
D
N
M
L
E
Y
K
S
W
L
K
N
L
A
Rhesus Macaque
Macaca mulatta
XP_001083428
653
75432
Y540
D
K
N
G
N
V
E
Y
M
S
S
F
Q
N
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35655
650
75039
S538
V
T
I
D
S
S
G
S
V
D
Y
M
S
S
F
Rat
Rattus norvegicus
Q3SWT6
640
73948
S527
V
S
T
D
S
S
G
S
V
D
Y
M
S
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
L198
H
E
G
P
M
C
D
L
L
W
S
D
P
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
N606
A
R
L
G
T
D
G
N
V
E
Y
E
S
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
A540
A
I
F
N
I
I
D
A
D
N
S
G
E
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741091
707
80312
R577
K
W
S
D
C
V
E
R
I
T
G
L
N
L
P
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
E568
M
N
E
N
G
L
I
E
Y
D
S
C
L
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
95
N.A.
N.A.
70.4
71.8
N.A.
N.A.
20.6
N.A.
50.9
N.A.
39.9
N.A.
40.5
44.5
Protein Similarity:
100
60.5
97.8
N.A.
N.A.
85.1
85.4
N.A.
N.A.
30.9
N.A.
68.9
N.A.
59.6
N.A.
58.2
63.9
P-Site Identity:
100
6.6
93.3
N.A.
N.A.
0
0
N.A.
N.A.
6.6
N.A.
6.6
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
6.6
100
N.A.
N.A.
20
20
N.A.
N.A.
33.3
N.A.
20
N.A.
33.3
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
10
0
0
0
0
0
10
0
10
0
% C
% Asp:
20
10
0
30
0
10
20
0
10
30
0
10
0
10
10
% D
% Glu:
0
10
10
0
0
10
30
10
0
10
0
10
10
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
20
0
0
30
% F
% Gly:
0
0
10
30
10
0
30
0
0
0
10
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
10
10
0
10
0
0
0
0
10
20
% I
% Lys:
10
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% K
% Leu:
0
0
10
0
10
10
0
10
10
0
10
10
10
20
0
% L
% Met:
10
0
0
10
10
0
0
0
20
0
0
20
0
0
10
% M
% Asn:
0
10
30
20
20
0
0
10
0
10
0
0
20
20
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
20
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
20
20
0
20
10
20
50
0
30
20
0
% S
% Thr:
0
10
10
0
10
0
0
0
0
10
0
0
0
0
10
% T
% Val:
20
0
0
0
0
30
0
0
30
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
20
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
20
10
0
30
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _