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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF1
All Species:
20.61
Human Site:
Y381
Identified Species:
50.37
UniProt:
O14829
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14829
NP_006231.2
653
75792
Y381
T
C
R
G
G
G
C
Y
F
G
P
D
V
T
S
Chimpanzee
Pan troglodytes
XP_526584
753
86517
Y466
T
I
R
G
G
G
C
Y
F
G
P
D
V
T
Q
Rhesus Macaque
Macaca mulatta
XP_001083428
653
75432
Y381
T
G
R
G
G
G
C
Y
F
G
P
D
V
T
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35655
650
75039
Y382
T
S
R
G
G
G
C
Y
F
G
P
D
V
T
S
Rat
Rattus norvegicus
Q3SWT6
640
73948
Y371
T
S
R
G
G
G
C
Y
F
G
P
D
V
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
E42
A
K
E
I
L
T
K
E
S
N
V
Q
E
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
Y450
S
F
R
G
G
G
C
Y
F
G
P
D
V
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
I378
H
D
N
K
I
I
T
I
F
S
A
S
N
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741091
707
80312
E402
P
P
V
N
K
G
M
E
S
E
K
E
N
S
A
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
L380
L
A
K
H
G
I
D
L
L
I
R
S
H
E
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
95
N.A.
N.A.
70.4
71.8
N.A.
N.A.
20.6
N.A.
50.9
N.A.
39.9
N.A.
40.5
44.5
Protein Similarity:
100
60.5
97.8
N.A.
N.A.
85.1
85.4
N.A.
N.A.
30.9
N.A.
68.9
N.A.
59.6
N.A.
58.2
63.9
P-Site Identity:
100
86.6
93.3
N.A.
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
80
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
86.6
93.3
N.A.
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
86.6
N.A.
6.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
60
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
60
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
20
0
10
0
10
10
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
0
10
0
60
70
70
0
0
0
60
0
0
0
0
0
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
10
10
20
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
10
10
10
10
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
10
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
10
0
0
20
0
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
60
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
20
% Q
% Arg:
0
0
60
0
0
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
10
20
0
0
0
0
0
0
20
10
0
20
0
10
40
% S
% Thr:
50
0
0
0
0
10
10
0
0
0
0
0
0
60
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
10
0
60
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _