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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF1
All Species:
11.52
Human Site:
S587
Identified Species:
28.15
UniProt:
O14829
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14829
NP_006231.2
653
75792
S587
T
D
H
S
G
L
I
S
V
E
E
F
R
A
M
Chimpanzee
Pan troglodytes
XP_526584
753
86517
S673
S
D
H
S
G
F
I
S
L
D
E
F
R
Q
T
Rhesus Macaque
Macaca mulatta
XP_001083428
653
75432
S587
T
D
H
S
G
L
I
S
I
E
E
F
R
A
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35655
650
75039
G585
I
I
D
S
D
Q
S
G
L
I
S
M
D
E
F
Rat
Rattus norvegicus
Q3SWT6
640
73948
G574
I
I
D
T
D
Q
S
G
L
I
S
M
D
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
M245
S
R
A
H
Q
L
V
M
E
G
Y
N
W
C
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
G653
I
I
D
K
D
H
S
G
Q
I
S
I
E
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
D587
L
N
G
D
G
K
V
D
L
N
E
F
L
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741091
707
80312
V624
H
A
Q
E
K
D
I
V
E
S
L
Y
R
H
K
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
S615
K
D
H
S
G
C
I
S
M
E
E
F
Q
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
95
N.A.
N.A.
70.4
71.8
N.A.
N.A.
20.6
N.A.
50.9
N.A.
39.9
N.A.
40.5
44.5
Protein Similarity:
100
60.5
97.8
N.A.
N.A.
85.1
85.4
N.A.
N.A.
30.9
N.A.
68.9
N.A.
59.6
N.A.
58.2
63.9
P-Site Identity:
100
60
93.3
N.A.
N.A.
6.6
0
N.A.
N.A.
6.6
N.A.
0
N.A.
20
N.A.
13.3
60
P-Site Similarity:
100
80
100
N.A.
N.A.
13.3
13.3
N.A.
N.A.
20
N.A.
0
N.A.
40
N.A.
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
0
0
0
20
20
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
40
30
10
30
10
0
10
0
10
0
0
20
10
0
% D
% Glu:
0
0
0
10
0
0
0
0
20
30
50
0
10
40
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
50
0
0
30
% F
% Gly:
0
0
10
0
50
0
0
30
0
10
0
0
0
0
0
% G
% His:
10
0
40
10
0
10
0
0
0
0
0
0
0
10
10
% H
% Ile:
30
30
0
0
0
0
50
0
10
30
0
10
0
0
0
% I
% Lys:
10
0
0
10
10
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
0
0
0
0
30
0
0
40
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
20
0
0
20
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
20
0
0
10
0
0
0
10
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
40
0
0
% R
% Ser:
20
0
0
50
0
0
30
40
0
10
30
0
0
0
0
% S
% Thr:
20
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
20
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _