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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHOX2A
All Species:
18.18
Human Site:
S269
Identified Species:
40
UniProt:
O14813
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14813
NP_005160.2
284
29653
S269
G
P
F
S
G
V
L
S
S
F
H
R
K
P
G
Chimpanzee
Pan troglodytes
A2T711
184
20085
A170
E
A
S
L
R
L
L
A
K
E
H
A
Q
A
M
Rhesus Macaque
Macaca mulatta
XP_001114806
280
28606
S265
G
P
F
S
G
V
L
S
S
F
H
R
K
P
G
Dog
Lupus familis
XP_542326
284
29643
S269
G
P
F
S
G
V
L
S
S
F
H
R
K
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62066
280
29399
S265
G
P
F
S
G
V
L
S
S
F
H
R
K
P
G
Rat
Rattus norvegicus
Q62782
281
29507
S266
G
P
F
S
G
V
L
S
S
F
H
R
K
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PVX0
317
34038
A297
D
P
R
N
T
S
I
A
S
L
R
M
K
A
K
Frog
Xenopus laevis
Q0IH87
483
53526
A426
E
P
P
T
A
V
S
A
S
C
S
Q
R
L
E
Zebra Danio
Brachydanio rerio
O42115
453
49378
A384
L
T
S
A
S
T
A
A
A
L
L
R
Q
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120833
319
33650
P304
R
P
F
S
A
A
L
P
P
Y
L
L
D
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797654
196
21310
G182
C
G
G
V
D
K
P
G
G
S
A
G
K
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32
81.6
98.9
N.A.
96.8
95.7
N.A.
N.A.
26.8
25.2
26.4
N.A.
N.A.
41
N.A.
21.1
Protein Similarity:
100
38.3
84.8
98.9
N.A.
96.8
96.1
N.A.
N.A.
37.2
34.5
35
N.A.
N.A.
50.4
N.A.
31.6
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
20
20
6.6
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
40
46.6
33.3
N.A.
N.A.
40
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
19
10
10
37
10
0
10
10
0
19
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
19
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
55
0
0
0
0
0
0
46
0
0
0
0
0
% F
% Gly:
46
10
10
0
46
0
0
10
10
0
0
10
0
10
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
10
0
0
0
64
0
10
% K
% Leu:
10
0
0
10
0
10
64
0
0
19
19
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
73
10
0
0
0
10
10
10
0
0
0
0
55
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% Q
% Arg:
10
0
10
0
10
0
0
0
0
0
10
55
10
0
0
% R
% Ser:
0
0
19
55
10
10
10
46
64
10
10
0
0
0
0
% S
% Thr:
0
10
0
10
10
10
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
10
0
55
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _