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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHOX2A
All Species:
4.55
Human Site:
S259
Identified Species:
10
UniProt:
O14813
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14813
NP_005160.2
284
29653
S259
K
A
W
Q
P
A
E
S
G
P
G
P
F
S
G
Chimpanzee
Pan troglodytes
A2T711
184
20085
A160
P
T
F
A
D
G
F
A
L
E
E
A
S
L
R
Rhesus Macaque
Macaca mulatta
XP_001114806
280
28606
S255
K
A
W
Q
P
A
E
S
G
P
G
P
F
S
G
Dog
Lupus familis
XP_542326
284
29643
P259
K
A
W
Q
P
A
E
P
G
P
G
P
F
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62066
280
29399
P255
K
A
W
Q
P
A
E
P
G
P
G
P
F
S
G
Rat
Rattus norvegicus
Q62782
281
29507
P256
K
A
W
Q
P
A
E
P
G
P
G
P
F
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PVX0
317
34038
D287
F
V
D
K
F
P
L
D
E
G
D
P
R
N
T
Frog
Xenopus laevis
Q0IH87
483
53526
G416
Y
A
L
S
P
L
T
G
G
L
E
P
P
T
A
Zebra Danio
Brachydanio rerio
O42115
453
49378
M374
F
G
R
L
F
S
S
M
G
P
L
T
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120833
319
33650
C294
G
G
G
A
W
G
S
C
S
P
R
P
F
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797654
196
21310
E172
A
L
G
K
E
W
R
E
D
L
C
G
G
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32
81.6
98.9
N.A.
96.8
95.7
N.A.
N.A.
26.8
25.2
26.4
N.A.
N.A.
41
N.A.
21.1
Protein Similarity:
100
38.3
84.8
98.9
N.A.
96.8
96.1
N.A.
N.A.
37.2
34.5
35
N.A.
N.A.
50.4
N.A.
31.6
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
26.6
13.3
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
33.3
26.6
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
55
0
19
0
46
0
10
0
0
0
10
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
10
10
0
10
0
0
0
10
% D
% Glu:
0
0
0
0
10
0
46
10
10
10
19
0
0
0
0
% E
% Phe:
19
0
10
0
19
0
10
0
0
0
0
0
55
0
0
% F
% Gly:
10
19
19
0
0
19
0
10
64
10
46
10
10
0
46
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
46
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
10
0
10
10
0
10
19
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
0
0
0
55
10
0
28
0
64
0
73
10
0
0
% P
% Gln:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
10
0
10
0
10
% R
% Ser:
0
0
0
10
0
10
19
19
10
0
0
0
19
55
10
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
0
10
0
10
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
46
0
10
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _