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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHOX2A All Species: 16.06
Human Site: S208 Identified Species: 35.33
UniProt: O14813 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14813 NP_005160.2 284 29653 S208 A S P R L S P S P L P V A L G
Chimpanzee Pan troglodytes A2T711 184 20085 G137 P G L P R L L G P G P G L Q A
Rhesus Macaque Macaca mulatta XP_001114806 280 28606 S204 A S P R L S P S P L P V A L G
Dog Lupus familis XP_542326 284 29643 S208 A S P R L S P S P L P A A L G
Cat Felis silvestris
Mouse Mus musculus Q62066 280 29399 S208 A S P R L S P S P L P A A L G
Rat Rattus norvegicus Q62782 281 29507 P208 L A S P L L S P S P L P A A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PVX0 317 34038 P249 G L P A S Y T P P P F L N S P
Frog Xenopus laevis Q0IH87 483 53526 N377 V P P S G P S N P M N P A I G
Zebra Danio Brachydanio rerio O42115 453 49378 P334 A F P G L A P P P N S S A L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120833 319 33650 S268 S V K Q H A V S D A P A A E G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797654 196 21310 T149 R E E L A L K T D L T E A R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32 81.6 98.9 N.A. 96.8 95.7 N.A. N.A. 26.8 25.2 26.4 N.A. N.A. 41 N.A. 21.1
Protein Similarity: 100 38.3 84.8 98.9 N.A. 96.8 96.1 N.A. N.A. 37.2 34.5 35 N.A. N.A. 50.4 N.A. 31.6
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 13.3 N.A. N.A. 13.3 26.6 46.6 N.A. N.A. 26.6 N.A. 13.3
P-Site Similarity: 100 13.3 100 93.3 N.A. 93.3 20 N.A. N.A. 20 46.6 53.3 N.A. N.A. 46.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 10 0 10 10 19 0 0 0 10 0 28 82 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % D
% Glu: 0 10 10 0 0 0 0 0 0 0 0 10 0 10 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 10 0 10 10 0 0 10 0 10 0 10 0 0 55 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 10 10 55 28 10 0 0 46 10 10 10 46 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 10 0 10 0 0 % N
% Pro: 10 10 64 19 0 10 46 28 73 19 55 19 0 0 19 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 10 0 0 37 10 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 10 37 10 10 10 37 19 46 10 0 10 10 0 10 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 10 0 0 0 0 % T
% Val: 10 10 0 0 0 0 10 0 0 0 0 19 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _