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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHOX2A
All Species:
18.18
Human Site:
S171
Identified Species:
40
UniProt:
O14813
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14813
NP_005160.2
284
29653
S171
K
K
G
E
A
R
C
S
S
E
D
D
D
S
K
Chimpanzee
Pan troglodytes
A2T711
184
20085
L100
G
A
V
A
A
P
R
L
P
E
A
P
A
L
P
Rhesus Macaque
Macaca mulatta
XP_001114806
280
28606
S167
K
K
G
E
A
R
C
S
S
E
D
D
D
S
K
Dog
Lupus familis
XP_542326
284
29643
S171
K
K
G
E
A
R
C
S
S
E
D
D
D
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q62066
280
29399
S171
K
K
G
E
A
R
C
S
S
E
D
D
D
S
K
Rat
Rattus norvegicus
Q62782
281
29507
S171
K
K
G
E
A
R
C
S
S
E
D
D
D
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PVX0
317
34038
G212
A
P
V
G
A
L
G
G
S
L
P
L
E
T
W
Frog
Xenopus laevis
Q0IH87
483
53526
H340
P
L
P
P
S
S
V
H
Q
S
L
P
S
N
P
Zebra Danio
Brachydanio rerio
O42115
453
49378
L297
P
L
A
A
A
H
P
L
S
H
Y
L
E
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120833
319
33650
P231
V
K
A
E
G
R
S
P
R
S
P
A
T
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797654
196
21310
Q112
G
L
H
E
K
R
K
Q
R
R
I
R
T
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32
81.6
98.9
N.A.
96.8
95.7
N.A.
N.A.
26.8
25.2
26.4
N.A.
N.A.
41
N.A.
21.1
Protein Similarity:
100
38.3
84.8
98.9
N.A.
96.8
96.1
N.A.
N.A.
37.2
34.5
35
N.A.
N.A.
50.4
N.A.
31.6
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
20
N.A.
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
26.6
13.3
20
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
19
73
0
0
0
0
0
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
46
46
46
0
0
% D
% Glu:
0
0
0
64
0
0
0
0
0
55
0
0
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
19
0
46
10
10
0
10
10
0
0
0
0
0
10
10
% G
% His:
0
0
10
0
0
10
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
46
55
0
0
10
0
10
0
0
0
0
0
0
0
46
% K
% Leu:
0
28
0
0
0
10
0
19
0
10
10
19
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
19
10
10
10
0
10
10
10
10
0
19
19
0
10
28
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
64
10
0
19
10
0
10
0
0
0
% R
% Ser:
0
0
0
0
10
10
10
46
64
19
0
0
10
46
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
19
19
0
% T
% Val:
10
0
19
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _